神经义肢在颈段脊髓损伤患者康复中的应用

doi:10.3969/j.issn.1006-9771.2017.04.006

Abstract

Abstract: Neural prosthesis control system is based on brain-computer interface and functional electrical stimulation technology, by analyzing the electroencephalograph control commands directly into the muscle system or an external device, which compensated efferent pathway from the brain-spinal cord, and recovered motor function of patients with cervical spinal cord injury. This paper described the basic structure, working principle and key technology of neural prosthetic system, summarized the application, problems and prospects of neural prosthetic technology in the rehabilitation of cervical spinal cord injury.

Key words: neural prosthesis, brain-computer interface, cervical spinal cord injury, rehabilitation, review

CLC Number:

R651.2

DIAO Zi-long, MA Xin-xin, CHAI Xiao-ke, BAI Ran, GONG Wei-jun. Application of Neural Prosthesis in Rehabilitation of Cervical Spinal Cord Injury (review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2017, 23(4): 394-397.

References

[1] Defronzo RA, Tripathy D. Skeletal muscle insulin resistance is the primary defect in type 2 diabetes [J]. Diabetes Care, 2009, 32(Suppl 2): S157-S163.
[2] Tam CS, Powe JE, Markovic TP, et al. The effects of high-fat feeding on physical function and skeletal muscle extracellular matrix [J]. Nutr Diabetes, 2015, 5: e187.
[3] Kang L, Lantier L, Kennedy A, et al. Hyaluronan accumulates with high-fat feeding and contributes to insulin resistance [J]. Diabetes, 2013, 62(6): 1888-1896.
[4] Kang L, Mayes WH, James FD, et al. Matrix metalloproteinase 9 opposes diet-induced muscle insulin resistance in mice [J]. Diabetologia, 2014, 57(3): 603-613.
[5] Kang L, Ayala JE, Lee-Young RS, et al. Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice [J]. Diabetes, 2011, 60(2): 416-426.
[6] Scheede-Bergdahl C, Bergdahl A, Schjerling P, et al. Exercise-induced regulation of matrix metalloproteinases in the skeletal muscle of subjects with type 2 diabetes [J]. Diab Vasc Dis Res, 2014, 11(5): 324-334.
[7] Gillies AR, Lieber RL. Structure and function of the skeletal muscle extracellular matrix [J]. Muscle Nerve, 2011, 44(3): 318-331.
[8] Grounds MD, Sorokin L, White J. Strength at the extracellular matrix-muscle interface [J]. Scand J Med Sci Sports, 2005, 15(6): 381-391.
[9] Berria R, Wang L, Richardson DK, et al. Increased collagen content in insulin-resistant skeletal muscle [J]. Am J Physiol Endocrinol Metab, 2006, 290(3): E560-565.
[10] Sishi B, Loos B, Ellis B, et al. Diet-induced obesity alters signalling pathways and induces atrophy and apoptosis in skeletal muscle in a prediabetic rat model [J]. Exp Physiol, 2011, 96(2): 179-193.
[11] Pincu Y, Linden MA, Zou K, et al. The effects of high fat diet and moderate exercise on TGFbeta1 and collagen deposition in mouse skeletal muscle [J]. Cytokine, 2015, 73(1): 23-29.
[12] Watts R, Mcainch AJ, Dixon JB, et al. Increased Smad signaling and reduced MRF expression in skeletal muscle from obese subjects [J]. Obesity (Silver Spring), 2013, 21(3): 525-528.
[13] Ge X, Vajjala A, Mcfarlane C, et al. Lack of Smad3 signaling leads to impaired skeletal muscle regeneration [J]. Am J Physiol Endocrinol Metab, 2012, 303(1): E90-102.
[14] Williams AS, Kang L, Wasserman DH. The extracellular matrix and insulin resistance [J]. Trends Endocrinol Metab, 2015, 26(7): 357-366.
[15] Solomon TP, Haus JM, Li Y, et al. Progressive hyperglycemia across the glucose tolerance continuum in older obese adults is related to skeletal muscle capillarization and nitric oxide bioavailability [J]. J Clin Endocrinol Metab, 2011, 96(5): 1377-1384.
[16] Kodama K, Horikoshi M, Toda K, et al. Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes [J]. Proc Natl Acad Sci U S A, 2012, 109(18): 7049-7054.
[17] Fogelstrand P, Boren J. Treatment of hyaluronan accumulation ameliorates high-fat diet-induced insulin resistance in mice [J]. Diabetes, 2013, 62(6): 1816-1817.
[18] Odegaard JI, Chawla A. Pleiotropic actions of insulin resistance and inflammation in metabolichomeostasis [J]. Science, 2013, 339(6116): 172-177.
[19] Zong H, Bastie CC, Xu J, et al. Insulin resistance in striated muscle-specific integrin receptor beta1-deficient mice [J]. J Biol Chem, 2009, 284(7): 4679-4688.
[20] Kang L, Mokshagundam S, Reuter B, et al. Integrin-linked kinase in muscle is necessary for the development of insulin resistance in diet-induced obese mice [J]. Diabetes, 2016, 65(6): 1590-1600.
[21] Mcdonald PC, Fielding AB, Dedhar S. Integrin-linked kinase－essential roles in physiology and cancer biology [J]. J Cell Sci, 2008, 121(Pt 19): 3121-3132.
[22] Gupta A, Bisht B, Dey CS. Focal adhesion kinase negatively regulates neuronal insulin resistance [J]. Biochim Biophys Acta, 2012, 1822(6): 1030-1037.
[23] Viglino C, Montessuit C. A role for focal adhesion kinase in the stimulation of glucose transport in cardiomyocytes [J]. J Cell Biochem, 2017, 118(4): 670-677.
[24] Lin D, Chun TH, Kang L. Adipose extracellular matrix remodelling in obesity and insulin resistance [J]. Biochem Pharmacol, 2016, 119: 8-16.
[25] Rodrigues SF, Tran ED, Fortes ZB, et al. Matrix metalloproteinases cleave the beta(2)-adrenergic receptor in spontaneously hypertensive rats [J]. Am J Physiol Heart Circ Physiol, 2010, 299(1): H25-H35.
[26] Delano FA, Schmid-Schonbein GW. Proteinase activity and receptor cleavage: mechanism for insulin resistance in the spontaneously hypertensive rat [J]. Hypertension, 2008, 52(2): 415-423.
[27] Tinahones FJ, Coin-Araguez L, Mayas MD, et al. Obesity-associated insulin resistance is correlated to adipose tissue vascular endothelial growth factors and metalloproteinase levels [J]. BMC Physiol, 2012, 12: 4.
[28] Hollborn M, Stathopoulos C, Steffen A, et al. Positive feedback regulation between MMP-9 and VEGF in human RPE cells [J]. Invest Ophthalmol Vis Sci, 2007, 48(9): 4360-4367.
[29] Tooke JE, Goh KL. Endotheliopathy precedes type 2 diabetes [J]. Diabetes Care, 1998, 21(12): 2047-2049.
[30] Rullman E, Norrbom J, Stromberg A, et al. Endurance exercise activates matrix metalloproteinases in human skeletal muscle [J]. J Appl Physiol (1985), 2009, 106(3): 804-812.
[31] Davis ME, Gumucio JP, Sugg KB, et al. MMP inhibition as a potential method to augment the healing of skeletal muscle and tendon extracellular matrix [J]. J Appl Physiol (1985), 2013, 115(6): 884-891.
[32] Hopps E, Lo Presti R, Montana M, et al. Gelatinases and their tissue inhibitors in a group of subjects with metabolic syndrome [J]. J Investig Med, 2013, 61(6): 978-983.
[33] Jaworski DM, Sideleva O, Stradecki HM, et al. Sexually dimorphic diet-induced insulin resistance in obese tissue inhibitor of metalloproteinase-2 (TIMP-2)-deficient mice [J]. Endocrinology, 2011, 152(4): 1300-1313.
[34] Kandalam V, Basu R, Abraham T, et al. TIMP2 deficiency accelerates adverse post-myocardial infarction remodeling because of enhanced MT1-MMP activity despite lack of MMP2 activation [J]. Circ Res, 2010, 106(4): 796-808.
[35] Menghini R, Menini S, Amoruso R, et al. Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice [J]. Gastroenterology, 2009, 136(2): 663-672.e4.

Application of Neural Prosthesis in Rehabilitation of Cervical Spinal Cord Injury (review)

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Metrics

Comments

Recommended 0

[1]	SHAO Weiting, LEI Jianghua. Effect of response interruption and redirection as a behavioral intervention on vocal stereotypy in children with autism spectrum disorder: a scoping review [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2024, 30(1): 10-20.
[2]	LUO Lihua, WANG Yusheng, LI Jianfeng, DONG Jige. Effect of early postoperative comprehensive rehabilitation on children and youth with supracondylar fracture of humerus complicated with ulnar nerve injury [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2024, 30(1): 105-110.
[3]	WANG Zihao, LI Xinhua, JIANG Huiping, GUO Sainan, LIANG Qiuman, SHI Tingqi. Short-term knee function after total knee arthroplasty and related factors [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2024, 30(1): 111-118.
[4]	WANG Hangyu, GE Keke, FAN Yonghong, DU Lilu, ZOU Min, FENG Lei. Effect of active music therapy on cognitive function for older adults with cognitive impairment: a systematic review based on ICD-11 and ICF [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2024, 30(1): 36-43.
[5]	WEN Jianing, JIN Qiuyan, ZHANG Qi, LI Jie, SI Qi. Effect of cognitively engaging physical activity on developing executive function of children and adolescents: a systematic review based on ICF [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2024, 30(1): 44-53.
[6]	GE Keke, FAN Yonghong, WANG Hangyu, DU Lilu, LI Changjiang, ZOU Min. Health benefit of mindfulness intervention for older adults with insomnia disorders: a systematic review [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2024, 30(1): 54-60.
[7]	CHEN Junwen, CHEN Qian, CHEN Cheng, LI Shuyue, LIU Lingling, WU Cunshu, GONG Xiang, LU Jun, XU Guangxu. Effect of modified Baduanjin exercise on cardiopulmonary function, motor function and activities of daily living for stroke patients [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2024, 30(1): 74-80.
[8]	ZHANG Jingya, ZOU Min, SUN Hongwei, SUN Changlong, ZHU Juntong. Effect of psychological intervention on anxiety or depression in children and adolescents with hearing impairment: a systematic review [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(9): 1004-1011.
[9]	WANG Junyu, YANG Yong, YUAN Xun, XIE Ting, ZHUANG Jie. Effect of high-intensity interval training on executive function for healthy children and adolescents: a systematic review [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(9): 1012-1020.
[10]	WEI Xiaowei, YANG Jian, WEI Chunyan. Psychological and behavioral benefits of adapted yoga exercise for children with autism spectrum disorder in special education schools: a systematic review [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(9): 1021-1028.
[11]	YANG Yaru, YANG Jian. School-based physical activity-related health services and their health benefits within the World Health Organization health-promoting school framework: a systematic review of systematic reviews [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(9): 1040-1047.
[12]	WANG He, HAN Liang, KAN Mengfan, YU Shaohong. Efficacy of electrical stimulation on shoulder-hand syndrome after stroke: a systematic review and meta-analysis [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(9): 1048-1056.
[13]	SHI Jiawei, LI Lingyu, YANG Haojie, WANG Qinlu, ZOU Haiou. Effect of preoperative prerehabilitation training on total knee arthroplasty: a systematic review of systematic reviews [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(9): 1057-1064.
[14]	CAI Huanian, FEI Sixian, ZHANG Yichen, SUN Qing, GUO Shuai, SONG Tao. Motion assistance analysis for robot-assisted tele-rehabilitation based on bilateral admittance control [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(9): 1104-1109.
[15]	JIANG Changhao, HUANG Chen, GAO Xiaoyan, DAI Yuanfu, ZHAO Guoming. Effect of neurofeedback training on cognitive function in the elderly: a systematic review [J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2023, 29(8): 903-909.