《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2017, Vol. 23 ›› Issue (5): 497-500.doi: 10.3969/j.issn.1006-9771.2017.05.001

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Concept and Pathophysiology of Post-polio Syndrome (review)

ZHANG Ai-min1, WANG Yu-ming2,3, GONG Hui-ming2,3, ZHANG Jun-yi4, SUN Qing2, ZHANG Ran2, LI Jing2   

  1. 1. Research Institute of Rehabilitation Information, China Rehabilitation Research Center, Beijing 100068, China;
    2. Department of Spinal and Neural Functional Reconstruction, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China;
    3. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China;
    4. Dongsheng People's Hospital, Erdos, Inner Mongolia 017000, China
  • Received:2016-11-23 Revised:2017-02-09 Published:2017-05-25 Online:2017-05-24
  • Contact: WANG Yu-ming. E-mail: wym.sq@163.com

Abstract: Post-polio syndrome (PPS) is a syndrome after acute infection of poliovirus and sequelae of polio. The incidence of PPS is high, and more in old patients. The pathological features of PPS include chronic nerve damage affected muscles, result in fatigue, pain, breathing and sleep disorders, fall risk, and so on, which impair their health and quality of life. The hypotheses of pathogenesis of PPS include over load of motor neurons, and the continuous existence of the poliovirus, etc. PPS is a stable neuromuscular disease progressing slowly.

Key words: post-polio syndrome, pathophysiology, review

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