A型肉毒毒素治疗痉挛型脑性瘫痪的疗效2年随访

doi:10.3969/j.issn.1006-9771.2017.07.017

Abstract

Abstract: ObjectiveTo investigate the long-term effect of Botulinum toxin type A (BTX-A) block on spasticity in cerebral palsy. MethodsFrom June, 2005 to December, 2013, 51 children with spastic cerebral palsy accepted routine rehabilitation with (trial group, n=24) or without (control group, n=27) BTX-A block. They were assessed with modified Ashworth Scale (MAS), Physician Rating Scale (PRS) and Gross Motor Function Measure (GMFM) before treatment, and with PRS and GMFM two years after treatment. ResultsThere was no significant difference between two groups in ages, body mass, and scores of MAS, PRS and GMFM before treatment (t<1.207, χ²=0.076, P>0.05). The scores of PRS and GMFM improved in both groups two years after treatment (t>2.217, P<0.05), and improved more in the trial group than in the control group (t>2.095, P<0.05). ConclusionThe long-term effect of BTX-A block is positive. The rehabilitation training after block can promote their motor function recovery.

Key words: cerebral palsy, spasticity, nerve block, Botilinum toxin type A, follow-up

CLC Number:

R742.3

LIU Jian-jun, QI Jing, ZHANG Yan, ZENG Fan-yong, LI Nan-ling, XI Bing-yu, WU Wei-hong. Effect of Botulinum Toxin Type A on Spastic Cerebral Palsy: Two Years Follow-up[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2017, 23(7): 816-819.

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Effect of Botulinum Toxin Type A on Spastic Cerebral Palsy: Two Years Follow-up

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