《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2019, Vol. 25 ›› Issue (3): 289-293.doi: 10.3969/j.issn.1006-9771.2019.03.008

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Effect of Acupuncture-rehabilitation Therapy on Homocysteine and Cognitive Function for Patients with Ischemic Stroke

GUAN Ying1,2, LI Ji2, WANG Lu2, ZHANG Li2, ZHU Lu-wen2, TANG Qiang2   

  1. 1.Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China
    2.Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150001, China
  • Received:2018-08-02 Revised:2018-12-10 Published:2019-03-25 Online:2019-04-02
  • Contact: TANG Qiang, E-mail: tangqiang1963@163.com
  • Supported by:
    National Natural Science Foundation of China (No. 81473762)

Abstract: Objective To investigate the effects of acupuncture-rehabilitation therapy on homocysteine (Hcy) and cognitive function in patients with cognitive impairment after ischemic stroke. Methods From July, 2017 to June, 2018, 88 patients with cognitive impairment after ischemic stroke were randomly divided into group A (n = 29, cluster needling), group B (n = 30, cognitive training) and group C (n = 29, acupuncture-rehabilitation). Their serum Hcy content was measured and they were assessed with Montreal Cognitive Assessment (MoCA) before and 30 days after treatment. Results The serum Hcy content was the least in group C after treatment (F = 6.570, P < 0.01), with the most score of MoCA (F = 31.526, P < 0.001). Conclusion Acupuncture-rehabilitation therapy is more effective than simple cluster needling or cognitive training for patients with cognitive impairment after ischemic stroke.

Key words: ischemic stroke, cognitive impairment, acupuncture-rehabilitation therapy, homocysteine

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