经颅直流电刺激作为一种成熟的非侵袭性脑刺激技术取得了显著的临床效果。目前有学者将直流电刺激技术应用到脊髓上，发现经皮脊髓直流电刺激可影响脊髓传导束及脊髓环路的电活动，从而起到治疗慢性疼痛及改善运动功能的作用。本文介绍经皮脊髓直流电刺激的生物学效应、安全性及潜在的临床意义。

As a kind of mature non-invasive brain stimulation technology, transcranial direct current stimulation (tDCS) has shown significance in clinic. Recently, DCS has been applied over the scalp to the spinal cord, named transcutaneous spinal direct current stimulation (tsDCS), that may modulate the spinal cord tracts and spinal cord loop electrical activity at segmental level, and may benefit in the treatment of chronic pain and motor dysfunction after injury of nervous system. This paper reviewed physiological effects, safety considerations and potential clinical applications of tsDCS.