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抗肌萎缩蛋白病患者心脏损伤的诊断和治疗进展

  • 罗思琦 ,
  • 吴士文
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  • 中国人民武装警察部队总医院神经内科,北京市 100039。
罗思琦(1992-),女,汉族,江西乐安县人,硕士研究生,主要研究方向:神经肌肉病。通讯作者:吴士文,男,博士,副主任医师。E-mail: neurowu@gmail.com。

收稿日期: 2016-12-20

  网络出版日期: 2017-03-31

基金资助

首都临床特色应用研究与成果推广项目(No.Z151100004015025)

Diagnosis and Treatment of Cardiac Involvement in Dystrophinopathies (review)

  • LUO Si-qi ,
  • WU Shi-wen
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  • Department of Neurology, General Hospital of Chinese Armed Police Forces, Beijing 100039, China

Received date: 2016-12-20

  Online published: 2017-03-31

摘要

抗肌萎缩蛋白病是一组致死性X染色体隐性遗传病。随着呼吸机等技术的应用,抗肌萎缩蛋白病患者的主要死亡原因从呼吸衰竭转变为循环衰竭,心脏问题的重要性日益突显。心肌损伤的诊断主要依靠心肌酶、心电图、超声心动图、心脏磁共振成像,治疗主要为抗慢性心衰药物,心脏移植以及左室支持装置植入术可能是终末期选择。

本文引用格式

罗思琦 , 吴士文 . 抗肌萎缩蛋白病患者心脏损伤的诊断和治疗进展[J]. 中国康复理论与实践, 2017 , 23(3) : 311 -314 . DOI: 10.3969/j.issn.1006-9771.2017.03.013

Abstract

Dystrophinopathies are a group of fatal X chromosome recessive genetic disease. With the application of ventilator technology, the main causes of death in patients with dystrophinopathies turned from respiratory failure into circulatory failure, and the importance of heart problems has become increasingly prominent. Myocardial damage can be defined with myocardial enzymes, electrocardiogram, ultrasound cardiogram, cardiac magnetic resonance imaging, etc. Drugs for chronic heart failure remain the most important strategy, and heart transplant or left ventricular assist devices implant may be the alternatives for those in the end.

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