[1] Dumont Y, Quirion R.NPY [M]// Kastin AJ. Handbook of Biologically Active Peptides. 2nd ed. Cambridge, Mass.: Academic Press, 2013: 883-888.
[2] Vähätalo LH, Ruohonen ST, Ailanen L, et al.Neuropeptide Y in noradrenergic neurons induces obesity in transgenic mouse models[J]. Neuropeptides, 2016, 55: 31-37.
[3] 董伟,宁炜,张翠珍, 等. 雌激素对去卵巢大鼠小脑皮质内脑源性神经营养因子及神经肽Y表达的影响[J]. 中国康复理论与实践, 2008, 14(11): 1033-1035.
[4] Schmeltzer SN, Herman JP, Sah R. Neuropeptide Y (NPY) and posttraumatic stress disorder (PTSD): a translational update[J]. Exp Neurol, 2016, 284: 196-210.
[5] Saraf R, Mahmood F, Amir R, et al.Neuropeptide Y is an angiogenic factor in cardiovascular regeneration[J]. Eur J Pharmacol, 2016, 776: 64-70.
[6] Pedragosa-Badia X, Stichel J, Beck-Sickinger AG.Neuropeptide Y receptors: how to get subtype selectivity[J]. Front Endocrinol (Lausanne), 2013, 4: 5.
[7] Sundström G, Xu B, Larsson TA, et al.Characterization of the neuropeptide Y system in the frog Silurana tropicalis (Pipidae): three peptides and six receptor subtypes[J]. Gen Comp Endocrinol, 2012, 177(3): 322-331.
[8] Michel MC, Beck-Sickinger A, Cox H, et al.XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors[J]. Pharmacol Rev, 1998, 50(1): 143-150.
[9] Yang Z, Han S, Keller M, et al.Structural basis of ligand binding modes at the neuropeptide Y Y 1 receptor[J]. Nature, 2018, 556(7702): 520-524.
[10] Wang Y, Wu Q, Hu M, et al. Ligand-and voltage-gated Ca2+ channels differentially regulate the mode of vesicular neuropeptide release in mammalian sensory neurons [J]. Sci Signal, 2017, 10(484): eaal1683.
[11] Brothers SP, Wahlestedt C.Therapeutic potential of neuropeptide Y (NPY) receptor ligands[J]. EMBO Mol Med, 2010, 2(11): 429-439.
[12] Lecat S, Belemnaba L, Galzi JL, et al.Neuropeptide Y receptor mediates activation of ERK1/2 via transactivation of the IGF receptor[J]. Cell Signal, 2015, 27(7): 1297-1304.
[13] Arcourt A, Gorham L, Dhandapani R, et al.Touch receptor-derived sensory information alleviates acute pain signaling and fine-tunes nociceptive reflex coordination[J]. Neuron, 2017, 93(1): 179-193.
[14] Usoskin D, Furlan A, Islam S, et al.Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing[J]. Nat Neurosci, 2015, 18(1): 145-153.
[15] 付淼,任浩,罗芳. 脉冲射频对坐骨神经慢性压迫大鼠降钙素基因相关肽表达的远期影响[J]. 中国康复理论与实践, 2018, 24(5): 526-529.
[16] Brumovsky P, Hofstetter C, Olson L, et al.The neuropeptide tyrosine Y1R is expressed in interneurons and projection neurons in the dorsal horn and area X of the rat spinal cord[J]. Neuroscience, 2006, 138(4): 1361-1376.
[17] Dumont Y, Chabot JG, Quirion R.Receptor autoradiography as mean to explore the possible functional relevance of neuropeptides: focus on new agonists and antagonists to study natriuretic peptides, neuropeptide Y and calcitonin gene-related peptides[J]. Peptides, 2004, 25(3): 365-391.
[18] Veyrat-Durebex C, Quirion R, Ferland G, et al.Aging and long-term caloric restriction regulate neuropeptide Y receptor subtype densities in the rat brain[J]. Neuropeptides, 2013, 47(3): 163-169.
[19] Peirs C, Williams SP, Zhao X, et al.Dorsal horn circuits for persistent mechanical pain[J]. Neuron, 2015, 87(4): 797-812.
[20] 王永刚,王栓科,时培晟,等. 神经肽Y在突出腰椎间盘组织中的表达及意义[J]. 中国疼痛医学杂志, 2012, 18(11): 663-666.
[21] Coronel MF, Villar MJ, Brumovsky PR, et al.Spinal neuropeptide expression and neuropathic behavior in the acute and chronic phases after spinal cord injury: Effects of progesterone administration[J]. Peptides, 2017, 88: 189-195.
[22] Naveilhan P, Hassani H, Lucas G, et al.Reduced antinociception and plasma extravasation in mice lacking a neuropeptide Y receptor[J]. Nature, 2001, 409(6819): 513-517.
[23] Solway B, Bose SC, Corder G, et al.Tonic inhibition of chronic pain by neuropeptide Y[J]. Proc Natl Acad Sci U S A, 2011, 108(17): 7224-7229.
[24] Lemons LL, Wiley RG.Neuropeptide Y receptor-expressing dorsal horn neurons: role in nocifensive reflex and operant responses to aversive cold after CFA inflammation[J]. Neuroscience, 2012, 216: 158-166.
[25] Kostić S, Puljak L, Sapunar D.Attenuation of pain-related behaviour evoked by carrageenan injection through blockade of neuropeptide Y Y1 and Y2 receptors[J]. Eur J Pain. 2013, 17(4): 493-504.
[26] Malet M, Leiguarda C, Gastón G, et al.Spinal activation of the NPY Y1 receptor reduces mechanical and cold allodynia in rats with chronic constriction injury[J]. Peptides, 2017, 92: 38-45.
[27] Taylor BK, Fu W, Kuphal KE, et al.Inflammation enhances Y1 receptor signaling, neuropeptide Y-mediated inhibition of hyperalgesia, and substance P release from primary afferent neurons[J]. Neuroscience, 2014, 256: 178-194.
[28] Taiwo OB, Taylor BK.Antihyperalgesic effects of intrathecal neuropeptide Y during inflammation are mediated by Y1 receptors[J]. Pain, 2002, 96(3): 353-363.
[29] 时培晟,王栓科,王永刚,等. 神经肽Y2 受体在大鼠神经病理性痛中的作用[J]. 中华麻醉学杂志, 2013, 33(5): 565-568.
[30] Bourane S, Duan B, Koch SC, et al.Gate control of mechanical itch by a subpopulation of spinal cord interneurons[J]. Science, 2015, 350(6260): 550-554.
[31] Braz J, Solorzano C, Wang X, et al.Transmitting pain and itch messages: a contemporary view of the spinal cord circuits that generate gate control[J]. Neuron, 2014, 82(3): 522-536.
[32] Wang JZ, Lundeberg T, Yu LC.Anti-nociceptive effect of neuropeptide Y in periaqueductal grey in rats with inflammation[J]. Brain Res, 2001, 893(1): 264-267.
[33] Martins-Oliveira M, Akerman S, Tavares I, et al.Neuropeptide Y inhibits the trigeminovascular pathway through NPY Y1 receptor: implications for migraine[J]. Pain, 2016, 157(8): 1666-1673.
[34] Alhadeff AL, Su Z, Hernandez E, et al.A neural circuit for the suppression of pain by a competing need state[J]. Cell, 2018, 173(1): 140-152.
[35] Cleary DR, Roeder Z, Elkhatib R, et al.Neuropeptide Y in the rostral ventromedial medulla reverses inflammatory and nerve injury hyperalgesia in rats via non-selective excitation of local neurons[J]. Neuroscience, 2014, 271: 149-159.
[36] Hartvigsen J, Hancock MJ, Kongsted A, et al.What low back pain is and why we need to pay attention[J]. Lancet, 2018, 391(10137): 2356-2367.
