综述

弥散张量成像在脑卒中患者运动功能预后评估中的研究进展

  • 谢运娟 ,
  • 廖伶艺 ,
  • 高强
展开
  • 1.四川大学,四川成都市 610041
    2.四川大学华西医院康复医学中心,四川成都市 610041
谢运娟(1996-),女,汉族,广东梅州市人,硕士研究生,主要研究方向:神经康复。

收稿日期: 2019-02-22

  修回日期: 2019-03-22

  网络出版日期: 2019-05-29

基金资助

四川省科技厅重点研发项目(No. 2018FZ0103)

Advance in Diffusion Tensor Imaging for Predicting Motor Function Outcome after Stroke

  • XIE Yun-juan ,
  • LIAO Ling-yi ,
  • GAO Qiang
Expand
  • 1.Sichuan University, Chengdu, Sichuan 610041, China
    2.Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

Received date: 2019-02-22

  Revised date: 2019-03-22

  Online published: 2019-05-29

Supported by

Sichuan Science and Technology Department Key Research and Development Projects (No. 2018FZ0103)

摘要

弥散张量成像可表征水分子扩散过程的取向特性,能有效观察和追踪脑白质纤维束。脑卒中患者各向异性分数下降表明纤维结构完整性受损,显著下降提示可能出现华勒变性;各向异性分数升高与运动功能恢复程度有关;患健侧各向异性分数比更适合成为脑卒中患者运动功能恢复预测指标。纤维束成像显示的皮质脊髓束变化,也可作为脑卒中患者运动功能结局的预测指标。

本文引用格式

谢运娟 , 廖伶艺 , 高强 . 弥散张量成像在脑卒中患者运动功能预后评估中的研究进展[J]. 中国康复理论与实践, 2019 , 25(5) : 546 -549 . DOI: 10.3969/j.issn.1006-9771.2019.05.008

Abstract

Diffusion tensor imaging (DTI) can be used to characterize the orientation of water diffusion, and track white matter fiber bundles. The decrease of fractional anisotropy after stroke indicates impairment of structural integrity of fibers, even Wallerian degeneration if serious; in another hand, the increase of fractional anisotropy relates to the more recovery of motor function. The affected/unaffected ratios of fractional anisotropy are more suitable for predicting motor function recovery after stroke. The changes of corticospinal tract in diffusion tensor tractography can also predict the motor outcome in stroke patients.

参考文献

1 KumarP, KathuriaP, NairP, et al. Prediction of upper limb motor recovery after subacute ischemic stroke using diffusion tensor imaging: a systematic review and meta-analysis [J]. J Stroke, 2016, 18(1): 50-59.
2 SterrA, DeanP J, SzameitatA J, et al. Corticospinal tract integrity and lesion volume play different roles in chronic hemiparesis and its improvement through motor practice [J]. Neurorehabil Neural Repair, 2014, 28(4): 335-343.
3 张晓钰. 弥散张量成像技术在评估脑卒中患者白质纤维束损伤及预后方面的研究进展[J]. 中国康复理论与实践, 2010, 16(6): 538-539.
4 AssafY, PasternakO. Diffusion tensor imaging (DTI)-based white matter mapping in brain research: a review [J]. J Mol Neurosci, 2008, 34(1): 51-61.
5 AyisS, WellwoodI, RuddA G, et al. Variations in health-related quality of life (HRQoL) and survival 1 year after stroke: five European population-based registers [J]. BMJ Open, 2015, 5(6): 1-9.
6 张丽华,米立新,郄淑燕. 弥散张量成像技术在脑卒中康复中的应用研究进展 [J]. 中国康复理论与实践, 2015, 21(7): 785-789.
7 高蓓瑶,白玉龙. 弥散张量成像在脑卒中康复中应用的研究进展[J]. 中国康复理论与实践, 2016, 22(9): 1031-1035.
8 JinJ F, GuoZ T, ZhangY P, et al. Prediction of motor recovery after ischemic stroke using diffusion tensor imaging: a meta-analysis [J]. World J Emerg Med, 2017, 8(2): 99-105.
9 SchaechterJ D, FrickerZ P, PerdueK L, et al. Microstructural status of ipsilesional and contralesional corticospinal tract correlates with motor skill in chronic stroke patients [J]. Hum Brain Mapp, 2009, 30(11): 3461-3474.
10 MaC, LiuA, LiZ, et al. Longitudinal study of diffusion tensor imaging properties of affected cortical spinal tracts in acute and chronic hemorrhagic stroke [J]. J Clin Neurosci, 2014, 21(8): 1388-1392.
11 BasserP J, PierpaoliC. Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. 1996 [J]. J Magn Reson, 2011, 213(2): 560-570.
12 BarrickT R, ClarkC A. Singularities in diffusion tensor fields and their relevance in white matter fiber tractography [J]. Neuroimage, 2004, 22(2): 481-491.
13 KloseU, MaderI, UnrathA, et al. Directional correlation in white matter tracks of the human brain [J]. J Magn Reson Imaging, 2004, 20(1): 25-30.
14 WerringD J, ClarkC A, ParkerG J, et al. A direct demonstration of both structure and function in the visual system: combining diffusion tensor imaging with functional magnetic resonance imaging [J]. Neuroimage, 1999, 9(3): 352-361.
15 ThomallaG, GlaucheV, KochM A, et al. Diffusion tensor imaging detects early Wallerian degeneration of the pyramidal tract after ischemic stroke [J]. Neuroimage, 2004, 22(4): 1767-1774.
16 WangR R, LiC, ZhangS, et al. Diffusion tensor imaging change in crus cerebri in striatocapsular infarction and correlation with upper extremity motor dysfunction [J]. Radiol Med, 2015, 120(11): 1064-1070.
17 杜鹏,张海燕. MRI纤维束成像在桥脑梗死后运动功能恢复中的临床研究[J]. 影像研究与医学应用, 2018, 2(18): 44-45.
18 PuigJ, PedrazaS, BlascoG, et al. Wallerian degeneration in the corticospinal tract evaluated by diffusion tensor imaging correlates with motor deficit 30 days after middle cerebral artery ischemic stroke [J]. Am J Neuroradiol, 2010, 31(7): 1324-1330.
19 王旭,刘斌,杨明,等. 扩散张量成像与急性脑干缺血性卒中患者运动功能预后的相关性[J]. 中国医学影像学杂志, 2014, 23(4): 255-259.
20 PuigJ, BlascoG, DaunisI E J, et al. Decreased corticospinal tract fractional anisotropy predicts long-term motor outcome after stroke [J]. Stroke, 2013, 44(7): 2016-2018.
21 KoyamaT, KoumoM, UchiyamaY. Utility of fractional anisotropy in cerebral peduncle for stroke outcome prediction: comparison of hemorrhagic and Ischemic strokes [J]. J Stroke Cerebrovasc Dis, 2017, 27(4): 878-885.
22 ByblowW D, StinearC M, BarberP A, et al. Proportional recovery after stroke depends on corticomotor integrity [J]. Ann Neurol, 2015, 78(6): 848-859.
23 WardN. Assessment of cortical reorganisation for hand function after stroke [J]. J Physiol, 2011, 589(Pt 23): 5625-5632.
24 PujolS, WellsW, PierpaoliC, et al. The DTI challenge: toward standardized evaluation of diffusion tensor imaging tractography for neurosurgery [J]. J Neuroimaging, 2015, 25(6): 875-882.
25 PuigJ, BlascoG, SchlaugG, et al. Diffusion tensor imaging as a prognostic biomarker for motor recovery and rehabilitation after stroke [J]. Neuroradiology, 2017, 59(4): 343-351.
26 KunimatsuA, AokiS, MasutaniY, et al. Three-dimensional white matter tractography by diffusion tensor imaging in ischaemic stroke involving the corticospinal tract [J]. Neuroradiology, 2003, 45(8): 532-535.
27 邵荣,张敏,刘澄英,等. 弥散张量纤维束成像技术在脑梗死患者运动功能康复中的临床研究[J]. 中华老年心脑血管病杂志, 2017, 19(11): 1176-1179.
28 ChoS H, KimS H, ChoiB Y, et al. Motor outcome according to diffusion tensor tractography findings in the early stage of intracerebral hemorrhage [J]. Neurosci Lett, 2007, 421(2): 142-146.
29 LindenbergR, RengaV, ZhuL L, et al. Structural integrity of corticospinal motor fibers predicts motor impairment in chronic stroke [J]. Neurology, 2010, 74(4): 280-287.
30 BigourdanA, MunschF, CoupeP, et al. Early fiber number ratio is a surrogate of corticospinal tract integrity and predicts motor recovery after stroke [J]. Stroke, 2016, 47(4): 1053-1059.
31 JangS H, KwonH G. Change of the anterior corticospinal tract on the normal side of the brain in chronic stroke patients: diffusion tensor imaging study [J]. Somatosens Mot Res, 2015, 32(1): 25-30.
32 ZhuL L, LindenbergR, AlexanderM P, et al. Lesion load of the corticospinal tract predicts motor impairment in chronic stroke [J]. Stroke, 2010, 41(5): 910-915.
33 DoughtyC, WangJ, FengW, et al. Detection and predictive value of fractional anisotropy changes of the corticospinal tract in the acute phase of a stroke [J]. Stroke, 2016, 47(6): 1520-1526.
34 StinearC M, BarberP A, PetoeM, et al. The PREP algorithm predicts potential for upper limb recovery after stroke [J]. Brain, 2012, 135(Pt 8): 2527-2535.
35 MarakaS, JiangQ, Jafari-KhouzaniK, et al. Degree of corticospinal tract damage correlates with motor function after stroke [J]. Ann Clin Transl Neurol, 2014, 1(11): 891-899.
36 YangM, YangY R, LiH J, et al. Combining diffusion tensor imaging and gray matter volumetry to investigate motor functioning in chronic stroke [J]. PLoS One, 2015, 10(5): 2-13.
37 BuchE R, RizkS, NicoloP, et al. Predicting motor improvement after stroke with clinical assessment and diffusion tensor imaging [J]. Neurology, 2016, 86(20): 1924-1925.
文章导航

/