《Chinese Journal of Rehabilitation Theory and Practice》 ›› 2019, Vol. 25 ›› Issue (2): 201-204.doi: 10.3969/j.issn.1006-9771.2019.02.013

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Application of Magnetic Resonance Spectroscopy in Clinic (review)

LIU Jun1, 2, 3, 4, 5, LI Jian-jun1, 2, 3, 4, 5, GAO Feng1, 2, 3, 4, 5, ZHANG Wen-hao1, 6, LIU Chang-bin1, 2, 3, 4, 5, LI Jun1, 2, 3, 4, 5, YANG De-gang1, 2, 3, 4, 5, ZHANG Xin1, 2, 3, 4, 5, ZHANG Chao1, 2, 3, 4, 5, QIN Chuan1, 2, 3, 4, 5   

  1. 1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
    2. Department of Spinal and Neural Function Reconstruction, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
    3. China Institute of Rehabilitation Science, Beijing 100068, China
    4. Center of Neural Injury and Repair, Beijing Institute for Brain Disorders, Beijing 100068, China
    5. Beijing Key Laboratory of Neural Injury and Rehabilitation, Beijing 100068, China
    6. Chinese Association of Rehabilitation Medicine, Beijing 100101, China
  • Received:2019-01-10 Revised:2019-01-30 Published:2019-02-25 Online:2019-04-01
  • Contact: LI Jian-juncorresponding author:. E-mail: crrc100@163.com
  • Supported by:
    China Rehabilitation Research Center Project (No. 2018ZX-05)

Abstract: Magnetic resonance spectroscopy (MRS) can directly and quantitatively analyze tissue metabolism. In the field of rehabilitation, it has been used in the prognosis of spinal cord injury, and observation of the metabolic changes after injury; in the diagnosis of stroke, cognitive dysfunction assessment, and dystonia mechanism research; exploring the rehabilitation mechanism of Parkinson's disease. It can be used in tumors for auxiliary diagnosis of prostate cancer and brain tumors. In addition, it can be used to assess the severity and prognosis of heat stroke, and to study the pathogenesis of Duchenne muscular dystrophy and multiple system atrophy. It was found in the animal experiments that it can optimize the experimental design. With the development of advanced shimming algorithms and other technologies, the limitations of MRS will be gradually broken.

Key words: rehabilitation field, magnetic resonance spectroscopy, medical field, basic research, review

CLC Number: