Research Progress of MicroRNA in Spinal Cord Injury (review)

  • ZHANG Wen-hao ,
  • LI Jian-jun ,
  • YANG De-gang ,
  • GAO Pin-cao ,
  • YANG Ming-liang ,
  • DU Liang-jie ,
  • GAO Feng ,
  • TANG Fang ,
  • LIU Chang-bin ,
  • LI Da-peng ,
  • ZHANG Xin ,
  • ZHANG Jie
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  • 1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China;
    2. Department of Spinal and Neural Function Reconstruction, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China;
    3. Center of Neural Injury and Repair, Beijing Institute for Brain Disorders, Beijing 100068, China;
    4. Beijing Key Laboratory of Neural Injury and Rehabilitation, Beijing 100068, China;
    5. Hunan Medical University, Huaihua, Hunan 418000, China

Received date: 2016-11-01

  Revised date: 2016-11-18

  Online published: 2017-06-27

Abstract

MicroRNAs are short non-coding RNAs that regulate and control the translation of target genes, and play an important role in gene expression involved in the development of spinal cord and spinal cord injury, which constitute novel targets for therapeutic intervention to promote repair and regeneration of the spinal cord, also they are the potential biomarkers of spinal cord injury. This article reviewed the mechanism of microRNAs and listed several microRNAs in spinal cord injury area.

Cite this article

ZHANG Wen-hao , LI Jian-jun , YANG De-gang , GAO Pin-cao , YANG Ming-liang , DU Liang-jie , GAO Feng , TANG Fang , LIU Chang-bin , LI Da-peng , ZHANG Xin , ZHANG Jie . Research Progress of MicroRNA in Spinal Cord Injury (review)[J]. Chinese Journal of Rehabilitation Theory and Practice, 2017 , 23(6) : 649 -653 . DOI: 10.3969/j.issn.1006-9771.2017.06.006

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