《中国康复理论与实践》

《中国康复理论与实践》 ›› 2004, Vol. 10 ›› Issue (12): 731-732.

• 专题 • 上一篇    下一篇

颈动脉粥样硬化与进展性卒中的相关因素研究

陈黔妹1,2; 沈扬1; 樊东升1   

  1. 1.北京大学第三医院神经内科 北京市 100083;2.清华大学第一附属医院神经内科 100016
  • 收稿日期:2004-08-27 出版日期:2004-12-25 发布日期:2004-12-25

Study of the relationship between carotid atherosclerosis and progressing stroke

CHEN Qian-mei, SHEN Yang, FAN Dong-sheng   

  1. Department of Neurology, The Third Hospital, Peking University, Beijing 100083, China
  • Received:2004-08-27 Published:2004-12-25 Online:2004-12-25

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被引次数

149

摘要： 目的探讨颈动脉粥样硬化与进展性卒中之间的相互关系。方法对103例发病24h内连续住院的脑梗死患者在住院1周内行颈动脉超声检查。对颈动脉内中膜厚度(IMT)、斑块情况及管腔狭窄与脑梗死早期进展之间的关系进行单因素及Logistic回归分析。 结果进展性脑卒中患者颈动脉斑块发生率、IMT显著高于非进展性脑卒中患者。Logistic回归分析显示 ,颈动脉斑块为脑梗死早期进展的危险因素,最大斑块的长度与厚度、颈动脉狭窄程度及IMT与卒中进展无明显关系。结论粥样斑块的结构与理化特性可能是引起脑梗死早期进展的原因。

关键词: 脑梗死, 预后, 颈动脉, 动脉粥样硬化

Abstract: ObjectiveTo investigate the relationship between carotid atherosclerosis and progressing stroke.Methods103 patients with acute cerebral infarction within the first 24 hours from onset were tested with carotid color doppler ultrasonography during the first week from admission. Univariate and multiple logistic regression analyses were performed to examine the relationship between carotid intima media thickness (IMT), plaque structure, the degree of artery stenosis and the early deterioration of cerebral infarction.ResultsPrevalence of carotid plaque and thickness of IMT in patients with progressing stroke were higher than that in non progressing patients. In logistic regression, presence of carotid plaque was independent predictors of progressing stroke. Plaque size, extent of artery stenosis and IMT were not included in the regression model.ConclusionPlaque structure and its chemical feature may be the cause of progressing stroke.

Key words: cerebral infarction, prediction, carotid, atherosclerosis