《中国康复理论与实践》

《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (02): 175-177.

• 临床研究 • 上一篇    下一篇

代谢综合征对心血管疾病预后的影响

王磊1; 陈光辉1; 王舒1; 王玉红2; 张琰琴1; 申长清3   

  1. 1.中国人民解放军总医院心内科实验室,北京市 100853;2.北京军区总医院263临床部,北京市 101149;3.解放军16医院内一科,新疆阿勒泰市 836500
  • 收稿日期:2007-12-13 出版日期:2008-02-01 发布日期:2008-02-01

Effect of Metabolic Syndrome on Prognosis of Patients with Cardiovascular Diseases

WANG Lei, CHENGuang-hui, WANG Shu, et al   

  1. The Laboratory of Cardiology Department, the General Hospital of PLA, Beijing 100853, China
  • Received:2007-12-13 Published:2008-02-01 Online:2008-02-01

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摘要： 目的观察代谢综合征(MS)对心血管疾病预后的影响。方法分析143例心血管疾病患者的临床资料,包括年龄、腰围、血压、体重指数、冠脉造影、心脏超声及血糖、总胆固醇、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、尿酸和肌酐等生理生化指标,了解MS的发生率,对比MS与非MS患者冠状动脉病变程度、器官功能衰竭、心室重构及心功能的改变。结果143例心血管疾病患者检出MS72例(50.35%),尿酸、肌酐、腰围、收缩压、舒张压、血糖、TG、体重指数、MS指数、HDL-C、左心室收缩末内径、射血分数、左前降支、室间隔厚度、左心室后壁厚度、左心室重量、左心室重量指数、心肌梗死、脑卒中、心功能不全、冠状动脉病变部位及狭窄程度与非MS组相比差异均具有统计学意义(P<0.05)。结论MS是多重心血管疾病危险因素的聚集,不仅使心血管疾病的患病率增加,并能影响其预后。

关键词: 代谢综合征, 冠心病, 器官功能衰竭, 冠脉造影, 超声

Abstract: Objective To evaluate the effect of metabolic syndrome(MS)on prognosis of patients with cardiovascular diseases(CVD).Methods The data of 143 CVD patients including the age,waistline,blood pressure,body mass index(BMI),coronary arteriongraphy,ultrasound and blood glucoset,total cholesterol(TC),triglycerides(TG),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),uric acid(UA),creatinine(Cr)were analyzed to detect the incidence of MS,the position and degree of coronary atherosclerosis,organ functional failure(OFF)and ventricular remodelling in the MS patients and those without MS.Results Of 143 CVD patients,72 cases(50.35%)were diagnosed with MS,and UA,Cr,waistline,systolic blood pressure(SBP),diastolic blood pressure(DBP),blood sugar,TG,body mass index(BMI),MS index,HDL-C,left ventricular end-systolic diameter(LVESD),ejection fraction(EF),left atrial dimension(LAD),interventricular septum thickness(IVST),posterior wall thickness(PWT),left ventricular mass(LVM),left ventricular mass index(LVMI),myocardial infraction(MI),stroke,cardia insufficiency,the position and degree of coronary atherosclerosis had difference between the patients with MS and without MS(P<0.05).Conclusion MS is a condition characterized by clustering of CVD risk factors.MS not only increases the incidence of CVD and OFF in the patients,but also effects the prognosis.

Key words: metabolic syndrome, coronary heart disease, organ functional failure, coronary arteriongraphy, ultrasound