《中国康复理论与实践》

《中国康复理论与实践》 ›› 2005, Vol. 11 ›› Issue (05): 379-380.

• 临床研究 • 上一篇    下一篇

癫痫儿童的认知功能及事件相关电位变化研究

赵建国1; 王金光2; 唐可欣1   

  1. 1.山东潍坊医学院 山东潍坊市 261042;2.山东潍坊学院 山东潍坊市 261061
  • 收稿日期:2005-01-30 出版日期:2005-05-25 发布日期:2005-05-25

Change of cognitive function and event-related potential for children with epilepsy

ZHAO Jian-guo, WANG Jin-guang, TANG Ke-xin   

  1. Weifang Medical College,Weifang 261042,Shandong, China
  • Received:2005-01-30 Published:2005-05-25 Online:2005-05-25

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被引次数

29

摘要： 目的探讨癫痫儿童的认知功能状况,观察其事件相关电位的变化。方法选择临床确诊的8～14岁癫痫患儿和相应年龄组正常儿童各45人,组成实验组和对照组,利用瑞文标准推理测验,分别对两组儿童进行认知功能测试,并分别测定其事件相关电位。结果癫痫儿童有智能缺陷者达33.3%,其B、E分量表得分显著低于正常对照组(P<0.05);事件相关电位P300 潜伏期较对照组显著延长(P<0.01)。结论癫痫可导致儿童智力受损,以抽象概念形成能力和类比能力受损最为明显。事件相关电位P300 潜伏期的变化是评价儿童智能状况很好的客观指标。

关键词: 癫痫, 认知功能, 事件相关电位, P300

Abstract: ObjectiveTo study the cognitive function and observe the changes of event-related potential of epileptic children.Methods45 epileptic children and 45 normal children were put in as the test group and the control group.The cognitive function and event-related potential were evaluated by means of Raven's standard Progressive Matrices (SPM) and evoked potential instrument respectively.ResultsAbout 33.3% epileptic children presented cognitive deficits.For children with cognitive deficits, their scores of B, E were significantly different from those in the control group(P<0.05).The latency of event-related potential P300 showed significantly prolonged than that of the control group (P<0.01).ConclusionEpilepsy may cause cognitive function deficit, especially in the ability of analog, analysis and abstract. The latency of event-related potential P300 is a very good objective to assess the cognitive function of children.

Key words: epilepsy, cognitive function, event-related potential, P300