《中国康复理论与实践》

《中国康复理论与实践》 ›› 2005, Vol. 11 ›› Issue (05): 397-397.

• 临床研究 • 上一篇    下一篇

复方丹参和施捷因联合治疗新生儿缺氧缺血性脑病

李文英; 傅万海; 何依绮   

  1. 广东省第二人民医院儿科 广东广州市 510317
  • 收稿日期:2004-10-13 出版日期:2005-05-25 发布日期:2005-05-25

Effect of monosialo gangliosides-1 and Radix salviae miltiorrhizae on hyposemic ischemic encephalopathy

LI Wen-ying, FU Wan-hai,HE Yi-qi   

  1. Department of Pediatrics, the Second People's Hospital of Guangdong Province, Guangzhou 510317, Guangdong,China
  • Received:2004-10-13 Published:2005-05-25 Online:2005-05-25

PDF (PC)

被引次数

6

摘要： 目的观察复方丹参(RSM)和施捷因(GM1)治疗新生儿缺氧缺血性脑病(HIE)的临床效果。方法62 例新生儿缺氧缺血性脑病患儿随机分为治疗组(31例)和对照组(31例),两组均采用常规治疗。治疗组在常规治疗基础上静脉滴注复方丹参0.5ml/kg,1次/d, 施捷因20 mg,1次/d,疗程7～14 d。结果治疗组显效25 例,有效5例。对照组显效10 例,有效14 例。两组显效率及总有效率比较有显著性差异(P<0.01)。结论在常规治疗的基础上加用复方丹参和施捷因,可提高新生儿缺氧缺血性脑病的治疗效果,且未发现毒副作用,值得临床推广应用。

关键词: 缺氧缺血性脑病, 新生儿, 施捷因, 复方丹参

Abstract: ObjectiveTo observe the effect of monosialo gangliosides-1 (GM-1) and Radix salviae miltiorrhizae (RSM) on neonatal hyposemic ischemic encephalopathy (HIE).Methods62 cases of HIE were randomly divided into treatment group and control group, and both groups received conventional therapy. Injection of RSM and GM-1 were added into the treatment group in 7～10 days therapy. ResultsHigh curative effect, average curative effect and total curative effect in the treatment group of 31 cases were 80.6%, 16.1% and 96.8%, while that in control group of 31 cases were 32.3%, 51.6% and 83.9% respectively. There was significant difference in the high curative effect and total effect between the two groups (P<0.05). ConclusionThe treatment combined with RSM and GM-1 can enhance the curative effect on HIE without any side effect.

Key words: hyposemic ischemic encephalopathy, neonatal, monosialo gangliosides-1, Radix salviae miltiorrhizae