《中国康复理论与实践》

《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (01): 75-77.

• 临床研究 • 上一篇    下一篇

人巨细胞病毒感染对非特异性下腰痛患者内皮功能的影响

吴建贤1; 王斌1; 李红2; 胡勇3; 胡雪莹3; 王明丽3   

  1. 1.安徽医科大学第一附属医院康复医学科,安徽合肥市 230022;2.安徽省立儿童医院小儿神经康复科,安徽合肥市 230051;3.安徽医科大学基础医学院病原学教研室,安徽合肥市 230031
  • 收稿日期:2006-09-28 出版日期:2007-01-01 发布日期:2007-01-01

Human Cytomegalovirus Infection and Endothelial Function Disorder in Patients with Nonspecific Low Back Pain

WU Jian-xian ,WANG Bing, LI Hong, et al.   

  1. Department of Rebabilitation Medicine, Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui, China
  • Received:2006-09-28 Published:2007-01-01 Online:2007-01-01

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摘要： 目的探讨内皮功能异常与人巨细胞病毒(HCMV)感染致非特异性下腰痛(NLBP)的关系,及其在NLBP发病中的作用。方法NLBP组50例,对照组36例,检测尿沉渣HCMV-DNA和包涵体,外周血HCMV-IgM、IgG和内皮素水平。结果NLBP组尿HCMV-DNA和包涵体,血HCMV-IgM、IgG阳性率高于正常对照组(P<0.05)。NLBP组内皮素水平增高(P<0.05)。结论NLBP常伴有HCMV感染及内皮功能异常。

关键词: 非特异性下腰痛(NLBP), 人巨细胞病毒(HCMV), 内皮素(ET)

Abstract: ObjectiveTo study the relationship between Human Cytomegalovirus (HCMV) infection and endothelial function disorder and its possible role in nonspecific low back pain (NLBP).MethodsHCMV-DNA, -IgM, -IgG, HE stain, endothelin (ET) were detected in 50 patients with NLBP and 36 healthy people without NLBP(non-NLBP group).ResultsThe positive rate of HCMV-DNA,-IgM,-IgG, HE stain were higher in NLBP group than that in non-NLBP group(P<0.05), as well as the levels of ET(P<0.05).ConclusionHCMV infection may relate with NLBP, and ET may play an important role in it.

Key words: nonspecific low back pain (NLBP), Human Cytomegalovirus (HCMV), endothelin (ET)