《中国康复理论与实践》

《中国康复理论与实践》 ›› 2006, Vol. 12 ›› Issue (06): 509-510.

• 临床研究 • 上一篇    下一篇

营养状况对慢性阻塞性肺病患者肺功能的影响

张颖   

  1. 中国医科大学附属第四医院西院门诊内科 辽宁沈阳市 110001
  • 收稿日期:2006-03-15 出版日期:2006-06-25 发布日期:2006-06-25

Effect of Nutritional Status on Pulmonary Function of Patients with Chronic Obstructive Pulmonary Disease

ZHANG Ying   

  1. The Outpatient Department of Internal Medicine, Western Branch of the Fourth Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning, China
  • Received:2006-03-15 Published:2006-06-25 Online:2006-06-25

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摘要： 目的探讨营养状况稳定期慢性阻塞性肺病(COPD)患者对肺功能和呼吸肌力、驱动指标的影响。方法对79例稳定期COPD患者进行营养状况评估和常规肺功能和呼吸肌力、驱动指标检查,并与53例同龄和同性别的健康人(对照组)比较。结果COPD患者的各项营养状况指标均明显低于对照组(P<0.05～0.01)。对照组的FEV1、FVC%、FEV1%、FVC和FEV1%/FVC%等常规肺功能指标均明显高于营养状况一般组和营养状况较差组COPD患者,营养状况一般组COPD患者的指标高于营养状况较差组(P<0.05～0.01)。对照组的PmiP、PmEP等呼吸肌力指标均明显高于营养状况一般组和营养状况较差组COPD患者,而P0.1驱动指标也明显低于后两者,营养状况较差组COPD患者的PmiP、PmEP值明显低于营养状况一般组,P0.1值明显高于营养状况一般组(P<0.05～0.01)。结论稳定期COPD患者常伴有营养不良,而营养状况可影响患者肺功能和呼吸肌力、驱动指标的减退程度。

关键词: 慢性阻塞性肺病, 稳定期, 营养不良, 肺功能, 呼吸肌力

Abstract: ObjectiveTo investigate the effect of nutritional status on the parameters of pulmonary function, respiratory muscle strength and drive in patients with chronic obstructive pulmonary disease (COPD).MethodsThe nutritional status of 79 COPD patients at stable period was evaluated regularly, and their pulmonary function and parameters of respiratory muscle strength and drive were examined routinely, and the results were compared with 53 healthy subjects (control group) of the same age and gender.ResultsThe indexes of nutritional status in the COPD patients were all obviously lower than those in the control group (P<0.05～0.01). The parameters of pulmonary function including FEV1, FVC, FEV1%, FVC% and FEV1%/FVC% in the control group were all markedly higher than those in the common nutritional status group and bad nutritional status group, and those were higher in the common nutritional status group than in the bad nutritional status group (P<0.05～0.01). The parameters of respiratory muscle strength including maximal mouth inspiratory pressure (Pmip) and maximal mouth expiratory pressure (PmEp) in the control group were obviously higher than those in the common nutritional status group and bad nutritional status group, but the drive parameter of P0.1 was markedly lower than those in the latter two groups, the Pmip and PmEp in the bad nutritional status group were obviously lower than those in the common nutritional status group, but the P0.1 was obviously higher than that in the common nutritional status group (P<0.05～0.01).ConclusionCOPD patients at stable period are often accompanied by malnutrition, and the nutritional status is decisive to the declined degrees of the parameters of pulmonary function, respiratory muscle strength and drive.

Key words: chronic obstructive pulmonary disease (COPD), stable period, malnutrition, pulmonary function, respiratory muscle strength