《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (05): 446-449.

• 综述 • 上一篇    下一篇

脑胶质瘤的分子生物学研究进展

石剑锋 综述; 马晓东 审校   

  1. 解放军总医院神经外科,北京市 100853
  • 收稿日期:2006-11-30 出版日期:2007-05-01 发布日期:2007-05-01

Advances in Molecular Biology in Gliomas(review)

SHI Jian-feng, MA Xiao-dong   

  1. Department of Neurosurgery, the General Hospital of PLA,Beijing 100853,China
  • Received:2006-11-30 Published:2007-05-01 Online:2007-05-01

摘要: 脑胶质瘤是中枢神经系统发生率最高的恶性肿瘤。近年来,脑胶质瘤发病的相关分子机制和凋亡研究已得到了深入而广泛的研究,为胶质瘤的分子病因、恶性进展、分子分型、基因治疗及预后评估研究提供有价值的参考依据。本文介绍了在该领域的相关研究进展。

关键词: 胶质瘤, 分子生物学, 凋亡, 综述

Abstract: Malignant gliomas represent the largest group of brain tumors in humans. Recent studies have explored the molecular changes and apoptosis on gliomas, which involved the molecular etiology malignant progression, molecular subtyping, gene therapy, and prognostic evaluation of gliomas. This paper reviewed the relevant advances in the field of gliomas molecular biology.

Key words: gliomas, molecular biology, apoptosis, review