《中国康复理论与实践》

《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (03): 286-286.

• 临床观察 • 上一篇    下一篇

小剂量奋乃静治疗老年痴呆精神病性症状的临床观察

施莹娟; 王峰; 何敏慧   

  1. 上海市普陀区精神卫生中心,上海市 200065
  • 收稿日期:2007-10-10 出版日期:2008-03-01 发布日期:2008-03-01

Application of Perphenazine to Treat Psychotic Symptoms of Senile Dementia:31 Case Report

SHI Ying-juan,WANG Feng, HE Ming-hui   

  1. Shanghai Putuo Mental health Center, Shanghai 200065, China
  • Received:2007-10-10 Published:2008-03-01 Online:2008-03-01

PDF (PC)

被引次数

4

摘要： 目的探讨小剂量奋乃静(2～6mg)治疗老年痴呆精神病性症状的临床疗效和安全性。方法对31例老年痴呆(阿尔茨海默病和血管性痴呆)伴精神病性症状患者在常规治疗的基础上加用小剂量奋乃静治疗。分别采用老年临床评定量表(SCAG)评定疗效,副反应量表(TESS)评定药物不良反应。结果治疗第8周末显著进步2例,进步22例,无效7例,不良反应轻微。结论小剂量奋乃静治疗老年痴呆精神病性症状安全、有效。

关键词: 奋乃静, 老年, 痴呆, 精神病性症状

Abstract: Objective To observe the effect of small dosage of perphenazine(2～6 mg)on psychotic symptoms of senile dementia.Methods 31 senile cases with psychotic symptoms after dementia(Alzheimer disease or vascular dementia)accepted small dosage of perphenazine in addition of the conventional therapy.They were assessed with Sadoz Clinical Assessment Geriatric(SCAG)and Treatment Emergent Symptom Scale(TESS).Results The score decreased 50%～75%(markedly improved)in 2 cases,25%～50%(improved)in 22 cases,lower than 25%(no improved)in 7 cases.Some mild emergent symptoms have been observed.Conclusion Small dosage of perphenazine is safe and effective in treating psychotic symptoms of senile dementia.

Key words: perphenazine, senile, dementia, psychotic symptoms