《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (04): 374-375.

• 临床研究 • 上一篇    下一篇

渐进抗阻训练结合阿仑膦酸钠提高绝经后骨质疏松症患者腰椎骨密度的初步研究

胡鸢; 唐金树; 侯树勋; 吴闻文; 郭继东; 石秀秀   

  1. 解放军总医院第一附属医院骨科,北京市 100037
  • 收稿日期:2007-11-22 出版日期:2008-04-01 发布日期:2008-04-01

Effect of Progressive Resistance Exercises Combined with Alendronate Sodium on Bone Mineral Density of Lumbar Spine in Patients with Postmenopausal Osteoporosis

HU Yuan, TANG Jin-shu, HOU Shu-xun, et al.   

  1. The Department of Orthopedics, the First Affiliated Hospital of the General Hospital of PLA, Beijing 100037, China
  • Received:2007-11-22 Published:2008-04-01 Online:2008-04-01

摘要: 目的观察渐进抗阻训练结合阿仑膦酸钠疗法对提高绝经后骨质疏松症患者腰椎骨密度的效果。方法20例绝经后骨质疏松症患者随机分为A、B两组,各10例,A组接受渐进抗阻训练结合阿仑膦酸钠治疗,B组仅接受阿仑膦酸钠治疗,疗程均为3个月。治疗前后用双能X线吸收仪分别测量腰椎骨密度。结果治疗前,两组患者的骨密度差异无显著性意义;治疗3个月后,A组患者的腰椎骨密度提高(4.520±0.68)%,B组提高(0.100±0.01)%,两组间的差异有非常显著性意义(P<0.01)。结论渐进抗阻训练结合阿仑膦酸钠疗法可提高绝经后骨质疏松症患者腰椎的骨密度,效果明显优于单纯服用阿仑膦酸钠。

关键词: 绝经后骨质疏松症, 渐进抗阻训练, 阿仑膦酸钠, 骨密度

Abstract: Objective To observe the effect of progressive resistance exercise combined with alendronate sodium on bone mineral density(BMD)of lumbar spine in patients with postmenopausal osteoporosis.Methods 20 patients with postmenopausal osteoporosis were randomly divided into the A and B group with 10 cases in each group.The cases of the group A were treated with progressive resistance exercises combined with alendronate sodium.Those of the group B only took alendronate sodium orally.The course of two groups was 3 months.BMD of lumbar spine was measured by dual-energy X-ray absorptiometry before and 3 months after treatment.Results Before treatment,BMD of two groups was not different.After 3 months treatment,BMD of lumbar spine were significantly improved in group A(raised 4.520±0.68%)than group B(raised 0.100±0.01%),there was a significant difference between two groups(P<0.01).Conclusion Progressive resistance exercises combined with alendronate is more efficacious than alendronate alone in restoring lumbar spine BMD in patients with postmenopausal osteoporosis.

Key words: postmenopausal osteoporosis, progressive resistance exercise, alendronate sodium, bone mineral density