《中国康复理论与实践》

《中国康复理论与实践》 ›› 2008, Vol. 14 ›› Issue (06): 506-507.

• 专题 • 上一篇    下一篇

甘油果糖复合神经阻滞治疗颈源性头痛的临床观察

申颖; 白莺; 金旭; 王保国   

  1. 首都医科大学附属北京天坛医院麻醉疼痛科,北京市 100050
  • 收稿日期:2008-05-18 出版日期:2008-06-01 发布日期:2008-06-01

Clinical Observation of Glycerol and Fructose Injection Combined with Nerve Block on Cervicogenic Headache

SHEN Ying, BAI Ying, JIN Xu, et al   

  1. The Department of Anesthesiology and Pain Management, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China
  • Received:2008-05-18 Published:2008-06-01 Online:2008-06-01

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摘要： 目的比较甘油果糖复合神经阻滞和单纯神经阻滞治疗颈源性头痛(CEH)的疗效和副作用。方法50例症状较重而无手术适应证的CEH患者随机分为神经阻滞组25例,应用得宝松、弥可保、利多卡因混合液于患侧C2椎旁、耳大、枕大、枕小神经阻滞;联合治疗组25例,在神经阻滞的同时每天应用甘油果糖注射液500ml静脉滴注,连续5d。比较两组患者治疗前和治疗后1d、1周、2周、3周、4周的疼痛评分(NRS)与颈椎活动度评分(ROM),以及肝功能、肾功能、电解质和血糖水平。结果神经阻滞组治疗后2周内NRS和ROM评分较治疗前明显降低(P<0.01),联合治疗组治疗后4周的NRS和ROM评分亦较治疗前明显降低(P<0.01),且各时间点的NRS和ROM评分均明显低于神经阻滞组(P<0.01)。结论甘油果糖复合神经阻滞治疗CEH安全、有效,是严重CEH患者较好的保守治疗方法。

关键词: 颈源性头痛, 神经阻滞, 甘油果糖注射液

Abstract: Objective To evaluate the effect of nerve block and nerve block combined with glycerol and fructose injection on cervicogenic headache (CEH).Methods 50 CEH patients were randomly divided into the nerve block group (n=25), received the occipital and C2 nerve block; nerve block combined with glycerol and fructose injection group (n=25), received nerve block plus glycerol and fructose injection. The pain degree (numeric rating scales, NRS) and the degree of cervical stiff measured by restriction of the range of motion of the neck (ROM) were recorded.Results NRS and ROM decreased significantly after treatment compared with the baseline in two groups ( P<0.01). NRS and ROM decreased much more in the nerve block combined with glycerol and fructose injection group than in the nerve block group ( P< 0.01).Conclusion Nerve block combined with glycerol and fructose injection is a more safe and effective method in the treatment of CEH.

Key words: cervicogenic headache, nerve block, glycerol and fructose injection