《中国康复理论与实践》

《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (07): 607-610.

• 专题　神经源性膀胱及不尿路管理 • 上一篇    下一篇

A型肉毒毒素在泌尿外科领域的应用

叶云龙1,2; 廖利民1,2   

  1. 1.首都医科大学康复医学院,北京市 100068;2.中国康复研究中心北京博爱医院泌尿外科,北京市 100068
  • 收稿日期:2007-04-26 出版日期:2007-07-01 发布日期:2007-07-01

Application of Botulinum Toxin Type A in Urological Field

YE Yun-long, LIAO Li-min   

  1. Schoolof Rehabilitation, CapitalMedical University, Department of Urology, Beijing Charity Hospital, China Rehabilitation Research Center, Beijing 100068, China
  • Received:2007-04-26 Published:2007-07-01 Online:2007-07-01

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摘要： A型肉毒毒素注射在大多数泌尿外科情况似乎都有积极的治疗作用,包括:逼尿肌-括约肌协同失调、排尿功能障碍、盆底疼痛、膀胱过度活动症、尿频-尿急综合征、间质性膀胱炎、良性前列腺增生,对于泌尿外科领域中许多下尿路功能障碍性疾病是一种新型、有前途的治疗方法。但是,仍需要进行深入的随机、双盲、安慰剂对照的研究,评价其临床有效性。

关键词: A型肉毒毒素, 泌尿外科, 综述

Abstract: Injection of botulinum toxin type A (BTX-A) seems to have a positive therapeutic effect in multiple urological conditions, including detrusor external sphincter dyssynergia, voiding dysfunction, painful pelvic floor, bladder overactivity, frequency-urgency syndrome, interstitial cystitis, benign prostatic hyperplasia, and be thought as a novel and promising treatment for a variety of lower urinary tract dysfunctions within the urological field. However, there is a long way to go to assess the clinical efficacy of this form by randomized, double blinded, placebo-controlled trials.

Key words: botulinum toxin type A, urology, review