《中国康复理论与实践》

《中国康复理论与实践》 ›› 2007, Vol. 13 ›› Issue (11): 1070-1071.

• 临床研究 • 上一篇    下一篇

精神病性症状及药物锥体外系副作用对平稳期精神分裂症患者主观生活质量的影响

朱辉1; 项玉涛1,2; 邓伟光2; Gabor S.Ungvari2   

  1. 1.首都医科大学附属北京安定医院12病区,北京市 100088;2香港中文大学临床医学院精神科学系
  • 收稿日期:2007-03-29 出版日期:2007-11-01 发布日期:2007-11-01

Impact of Symptomology and Drug-induced Extrapyramidal Side Effects on Subjective Quality of Life for Schizophrenic Outpatients

ZHU Hui, XIANG Yu-tao, TANG Wai-Kwong, et al   

  1. Ward12, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China
  • Received:2007-03-29 Published:2007-11-01 Online:2007-11-01

PDF (PC)

被引次数

2

摘要： 目的调查中国精神科门诊精神分裂症患者的主观生活质量,并探讨精神病性症状和药物锥体外系副作用和生活质量的关系。方法对符合研究条件的198例平稳期精神分裂症患者的精神病性症状、药物锥体外系副作用和其主观生活质量进行标准化测量。对数据进行多元逐步回归分析。结果药物锥体外系副作用对于患者生活质量的躯体领域有显著影响;阳性症状和焦虑症状对于患者生活质量的心理领域、社会领域和环境领域有重要影响。结论对于处于平稳期的精神分裂症患者,有效控制其阳性症状、焦虑症状和锥体外系副作用,能够改善患者的主观生活质量。

关键词: 精神分裂症, 主观生活质量, 阳性症状, 焦虑症状, 锥体外系副作用

Abstract: Objective To investigate the subjective quality of life(SQOL)in schizophrenia outpatients and explore the relationships among symptomology,drug-induced extrapyramidal side effects(EPS)and SQOL.Methods198 eligible subjects were recruited and interviewed using standard instruments.Multiple linear regression with stepwise method was used.ResultsEPS was found to significantly predict physical SQOL domain while anxiety and positive symptoms predicted psychological,social and environmental SQOL domains,respectively.ConclusionSQOL of schizophrenia outpatients could be improved if their anxiety and positive symptoms and EPS are effectively controlled.

Key words: schizophrenia, subjective quality of life, positive symptoms, anxiety, extrapyramidal side effects(EPS)