《中国康复理论与实践》 ›› 2012, Vol. 18 ›› Issue (6): 591-592.

• 论文 • 上一篇    下一篇

尿毒症患者周围神经的电生理研究

李萍,吴婷婷,乔慧   

  1. 首都医科大学附属北京天坛医院,北京市神经外科研究所神经电生理室,北京市100050。
  • 收稿日期:2012-03-12 修回日期:2012-05-05 出版日期:2012-06-25 发布日期:2012-06-25
  • 通讯作者: 乔慧

Studies of Peripheral Nerve Electrophysiology in Uremic Patients

LI Ping, WU Ting-ting, QIAO Hui.   

  1. Department of Electrophysiology, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing Neurosurgical Institute, Beijing 100050, China.
  • Received:2012-03-12 Revised:2012-05-05 Published:2012-06-25 Online:2012-06-25

摘要: 目的研究尿毒症患者周围神经的电生理表现。方法选择尿毒症患者24 例及同期健康对照者19 例,采用常规表面电极对胫后神经、腓总神经、腓肠神经及皮肤交感反应进行检查,观察尿毒症患者周围神经的电生理表现。结果两组运动传导、感觉传导及交感皮肤反应潜伏期均有显著性差异(P<0.05)。电生理表现主要为F 波的潜伏期延长,传导速度减慢,潜伏期延长,感觉纤维受累重于运动纤维。结论尿毒症性周围神经病是尿毒症最常见的并发症之一,神经电生理的异常明显早于临床症状,周围神经的电生理检查对该病的诊断及评价具有重要意义。

关键词: 尿毒症, 周围神经, 神经电生理, 神经传导

Abstract: Objective To analyze electrophysiology of peripheral nerve in uremic patients. Methods 24 uremic patients and 19 normalvolunteers were included, surface electrodes were used to observe the electrophysiology performance, including tibial nerve, peroneal nerve,sural nerve and skin sympathetic response. Results The motor conduction, sensory conduction and skin sympathetic response were significantlydifferent between uremia patients and normal volunteers (P<0.05). The electrophysiology performance showed that F wave latencyprolonged, nerve conduction slowed, distal latencies prolonged, sensory fibers damaged more serious than motor fibers. Conclusion Peripheralneuropathy is one of the most common complications in uremia patients, neural electrophysiological abnormalities are significantly earlierthan clinical symptoms, nerve electrophysiological examination is of great significance in diagnosis and evaluation uremic peripheralneuropathy.

Key words: uremic, peripheral nerve, electrophysiology, nerve conduction