《中国康复理论与实践》 ›› 2015, Vol. 21 ›› Issue (01): 65-068.

• 综述 • 上一篇    下一篇

脑外伤动物模型认知障碍评价方法研究进展

马登磊,张兰, 李林   

  1. 首都医科大学宣武医院药物研究室,神经变性病教育部重点实验室,北京市100053。
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2015-01-25 发布日期:2015-01-25

Advance in Cognitive Behavior Assessment for Traumatic Brain Injury Animal Models (review)

MA Deng-lei, ZHANG Lan, LI Lin.   

  1. Department of Pharmacology, Xuanwu Hospital, Capital Medical University; Beijing Academy for Brain Disorders, Beijing 100053, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-01-25 Online:2015-01-25

摘要: 认知障碍是脑外伤常见的后遗症之一。脑外伤动物模型目前广泛应用于基础和药物研究中,也出现了多种评价该模型的认知障碍评价的方法。本文综述近年来不同研究者对脑外伤动物模型认知障碍的行为学评价方法。

关键词: 脑外伤, 动物模型, 认知障碍, 行为学评价, 综述

Abstract: Cognitive dysfunction is common after traumatic brain injury (TBI). TBI animal models and cognitive behavior assessments are commonly used in the mechanism and pharmacology researches. This article reviewed the advance of methods of cognitive behavior assessment on TBI animal models.

Key words: traumatic brain injury, animal models, cognitive dysfunction, behavior assessment, review