《中国康复理论与实践》

《中国康复理论与实践》

• 专题 • 上一篇    下一篇

重复经颅磁刺激治疗脑卒中后执行功能障碍的研究进展①

刘远文1,2，潘翠环1，胡楠1，陈艳1，方杰1   

  1. 1. 广州医科大学附属第二医院康复医学科，广东广州市510260；2. 广州医科大学康复治疗学系，广东广州市511436。
  • 出版日期:2016-10-25 发布日期:2016-12-05

Advance in Repetitive Transcranial Magnetic Stimulation for Post-stroke Executive Impairment (review)

LIU Yuan-wen1,2, PAN Cui-huan1, HU Nan1, CHEN Yan1, FANG Jie1   

  1. 1. The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510260, China; 2. Department of Rehabilitation, Guangzhou Medical University, Guangzhou, Guangdong 511436, China
  • Published:2016-10-25 Online:2016-12-05

PDF (PC)

摘要： 执行功能障碍是脑卒中常见后遗症之一，严重影响患者生活质量。重复经颅磁刺激作为一种新型电生理技术，逐渐被用于探索脑卒中后执行功能障碍的临床治疗。本文就脑卒中后执行功能障碍的概况、重复经颅磁刺激的基本原理和作用机制、其改善脑卒中后执行功能障碍的临床应用和安全性等做一综述。临床研究表明高频刺激、低频刺激、联合其他治疗方法对执行障碍均有疗效。然而，重复经颅磁刺激治疗脑卒中后执行功能障碍的作用机制和最佳治疗方案尚无统一定论。

关键词: 脑卒中, 认知功能障碍, 执行功能障碍, 重复经颅磁刺激, 综述

Abstract: Executive impairment is one of the common sequelae of stroke, which seriously affects the quality of life of patients. Repetitive transcranial magnetic stimulation (rTMS), as a new type of electrophysiological technique, has been used in the clinical treatment of Post-Stroke Executive Impairment (PSEI). This paper summarized the survey of PSEI, the basic principle and mechanism of rTMS, clinical application of rTMS for PSEI and its safety. Clinical studies showed that high frequency stimulation, low frequency stimulation, and combination with other therapeutic methods were effective in PSEI. However, there was no unified theory about the mechanism and the best treatment plan of rTMS for PSEI.

Key words: stroke, cognitive impairment, executive impairment, repetitive transcranial magnetic stimulation, review