《中国康复理论与实践》 ›› 2017, Vol. 23 ›› Issue (4): 424-429.doi: 10.3969/j.issn.1006-9771.2017.04.013

• 临床研究 • 上一篇    下一篇

全麻下脊柱脊髓手术中神经电生理监测异常的原因分析

熊巍1a,2,王增春1a,2,张军卫1b,2,王强1a,2   

  1. 1.中国康复研究中心北京博爱医院,a.麻醉科,b.脊柱脊髓外科,北京市100068;
    2.首都医科大学康复医学院,北京市100068。
  • 收稿日期:2016-10-19 出版日期:2017-04-05 发布日期:2017-05-17
  • 通讯作者: 张军卫(1966-),男,汉族,辽宁铁岭市人,博士,主任医师,副教授,主要研究方向:脊柱脊髓外科疾病诊治。王强(1968-),男,汉族,浙江杭州市人,博士,主任医师,主要研究方向:临床麻醉与疼痛治疗。E-mail: 13801032889@163.com。
  • 作者简介:熊巍(1974-),女,汉族,北京市人,主治医师,主要研究方向:临床麻醉与疼痛治疗。
  • 基金资助:
    1.佳木斯大学研究生科技创新项目 (No.YZ2016_039);2.佳木斯大学校级科技创新项目(No.Cxtd-2013-02)。)

Analysis of Abnormalities of Intraoperative Neurophysiological Monitoring in Spine and Spinal Cord Surgery under General Anesthesia

XIONG Wei1a,2, WANG Zeng-chun1a,2, ZHANG Jun-wei1b,2, WANG Qiang1a,2   

  1. 1. a. Department of Anesthesiology, b. Department of Spine and Spinal Cord Surgery, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China;
    2. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
  • Received:2016-10-19 Published:2017-04-05 Online:2017-05-17
  • Contact: ZHANG Jun-wei, WANG Qiang. E-mail: 13910158172@163.com (ZHANG Jun-wei), 13801032889@163.com (WANG Qiang)

摘要: 目的  分析全麻下脊柱手术中影响神经电生理监测的因素,提高监测有效性。方法  对2011年7月至2016年1月在本院全麻下接受脊柱脊髓手术中实施体感诱发电位(SEP)及运动诱发电位(MEP)监测的患者资料进行回顾性分析。结果  收集到104例患者资料,其中18例出现SEP异常,17例出现MEP异常。单因素分析显示,SEP与吸入麻醉药浓度、围术期低体温、麻醉方式有关(χ2>6.219, P<0.05),而MEP异常与吸入麻醉药浓度、围术期低血压、追加肌松剂有关(χ2>4.125, P<0.05)。多因素非条件Logistic分析显示,吸入麻醉药浓度、围术期低体温对SEP异常有显著性影响(P<0.05),而吸入麻醉药浓度、围术期低血压对MEP异常有显著性影响(P<0.05)。结论  吸入麻醉药浓度、围术期低体温、围术期低血压可能是影响神经电生理监测的主要因素。

关键词: 脊柱脊髓手术, 全身麻醉, 术中神经电生理监测, 体感诱发电位, 运动诱发电位

Abstract: Objective To analyze the factors related with intraoperative neurophysiological monitoring (IONM) in spine and spinal cord surgery under general anesthesia, in order to increase the effectiveness of IONM. Methods A retrospective study was performed on patients who received somatosensory-evoked potential (SEP) and motor-evoked potentials (MEP) in spine surgery under general anesthesia from July, 2011 to January, 2016. Results Data from 104 patients were collected in which 18 cases had abnormal SEP and 17 cases had abnormal MEP. A single factor analysis indicated that abnormal SEP was related to concentration of inhalation anesthetic (CIA), hypothermia in perioperative period (HTM), and type of anesthesia (χ2>6.219, P<0.05), whereas abnormal MEP was related to CIA, hypotension in perioperative period (HTN), and additional muscular relaxants (χ2>4.125, P<0.05). Logistic regression analysis indicated that abnormal SEP was related to CIA and HTM, whereas abnormal MEP was related to CIA and HTN (P<0.05). Conclusion CIA, HTM, and HTN were possible factors related with IONM in spine surgery under general anesthesia.

Key words: spine and spinal cord surgery, general anesthesia, intraoperative neurophysiological monitoring, somatosensory-evoked potential, motor-evoked potentials

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