工作记忆与词汇学习：基于词图匹配任务的事件相关电位研究

doi:10.3969/j.issn.1006-9771.2019.00.001

《中国康复理论与实践》 ›› 2019, Vol. 25 ›› Issue (1): 70-75.doi: 10.3969/j.issn.1006-9771.2019.00.001

工作记忆与词汇学习：基于词图匹配任务的事件相关电位研究

樊瑞文, 史华伟, 黄幸, 段怿炜, 鄢鹤铭, 常静玲

北京中医药大学东直门医院神经内科,北京市 100700

收稿日期:2018-11-22 修回日期:2018-12-06 出版日期:2019-01-25 发布日期:2019-02-18
通讯作者: 常静玲(1970-),女,回族,博士,主任医师、教授,主要研究方向：中医药防治脑病的临床与神经影像学实验研究。E-mail: ear6979@163.com
作者简介:樊瑞文(1991-),女,汉族,江苏镇江市人,博士研究生,主要研究方向：中医药防治脑病的临床与神经影像学实验研究。
基金资助:
1.国家自然科学基金面上项目(No. 81473654); 2.国家中医药行业科研专项(No. 201407001-9); 3.北京市自然科学基金项目(No. 7181005)

Role of Working Memory in Lexical Access: An Event-related Potential Study Based on Word-picture Matching Tasks

FAN Rui-wen, SHI Hua-wei, HUANG Xing, DUAN Yi-wei, YAN He-ming, CHANG Jing-ling

Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China

Received:2018-11-22 Revised:2018-12-06 Published:2019-01-25 Online:2019-02-18
Contact: CHANG Jing-ling. E-mail: ear6979@163.com
Supported by:
National Natural Science Foundation of China (General) (No. 81473654), National Special Research Projects of Traditional Chinese Medicine (No. 201407001-9) and Beijing Natural Science Foundation (No. 7181005)

摘要/Abstract

摘要： 目的探究工作记忆在语言康复训练中的作用,为汉语语言康复提供客观评价手段。
方法 2017年12月至2018年6月,20例健康成年人完成词与图分屏呈现任务(任务1)和同屏呈现任务(任务2),比较在匹配与不匹配情况下事件相关电位(ERP) N400的特征。
结果最终纳入14例。任务1诱发的N400波峰出现更早,振幅更高;在中央顶枕部N400激活强度更大,且诱发更大的N170、P1波;两任务在多数脑区目标时段匹配与不匹配N400振幅差有显著性差异 (t > 2.319, P < 0.05)。
结论有工作记忆参与的词图匹配语言任务可更好地调动语言相关脑区处理信息。模拟汉语语言康复场景的实验任务可作为客观评价指标。

关键词: 语言康复, 词汇学习, 工作记忆, 事件相关电位, N400

Abstract: Objective To observe the role of working memory in the process of language, and provide an objective evaluation for Chinese language rehabilitation.
Methods From December, 2017 to June, 2018, 20 healthy subjects accepted word-picture matching tasks as the word and picture showed on the different (task 1) or same (task 2) screens, and their event-related potential of N400 were compared in matched and mismatched conditions.
Results Forteen subjects were included finally. Task 1 induced N400 appeared earlier with higher amplitude and more activation in central parietal occipital region, followed larger N170 and P1 wave. There were significant differences in most cerebral regions between the two tasks in N400 amplitude difference of matched and mismatched conditions (t > 2.319, P < 0.05).
Conclusion Word-picture matching tasks may involve more language-related brain regions with the intervention of working memory, that might work better in process of vocabulary. The tasks simulating the scene of Chinese language rehabilitation can be used as an objective evaluation for clinical activities.

Key words: language rehabilitation, lexical access, working memory, event-related potentials, N400

中图分类号:

R493

樊瑞文, 史华伟, 黄幸, 段怿炜, 鄢鹤铭, 常静玲. 工作记忆与词汇学习：基于词图匹配任务的事件相关电位研究[J]. 《中国康复理论与实践》, 2019, 25(1): 70-75.

FAN Rui-wen, SHI Hua-wei, HUANG Xing, DUAN Yi-wei, YAN He-ming, CHANG Jing-ling. Role of Working Memory in Lexical Access: An Event-related Potential Study Based on Word-picture Matching Tasks[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2019, 25(1): 70-75.

参考文献

[1] Lalor E C.Neuroscience: the rhythms of speech understanding[J]. Curr Biol, 2018, 28(3): R105-R108.
[2] Zhang Q, Yu B, Zhang J, et al.Probing the timing recruitment of Broca's area in speech production for mandarin Chinese: A TMS study[J]. Front Hum Neurosci, 2018, 12: 133.
[3] Havas V, Waris O, Vaquero L, et al.Morphological learning in a novel language: A cross-language comparison[J]. Q J Exp Psychol (Hove), 2015, 68(7): 1426-1441.
[4] Tamminen J, Davis M H, Rastle K.From specific examples to general knowledge in language learning[J]. Cogn Psychol, 2015, 79: 1-39.
[5] Baddeley A.Working memory: looking back and looking forward[J]. Nat Rev Neurosci, 2003, 4(10): 829-839.
[6] Ullman M T.The declarative/procedural model of lexicon and grammar[J]. J Psycholinguist Res, 2001, 30(1): 37-69.
[7] Cowan N.Working memory maturation: can we get at the essence of cognitive growth?[J]. Perspect Psychol Sci, 2016, 11(2): 239-264.
[8] Siciliano M, Trojano L, De Micco R, et al.Motor, behavioural, and cognitive correlates of fatigue in early, de novo Parkinson disease patients[J]. Parkinsonism Relat Disord, 2017, 45: 63-68.
[9] Cogan G B, Iyer A, Melloni L, et al.Manipulating stored phonological input during verbal working memory[J]. Nat Neurosci, 2017, 20(2): 279-286.
[10] Hickok G, Poeppel D.Towards a functional neuroanatomy of speech perception[J]. Trends Cogn Sci, 2000, 4(4): 131-138.
[11] Baddeley A.Working memory[J]. Science, 1992, 255(5044): 556-559.
[12] Bulut T, Cheng S, Xu K, et al.Is there a processing preference for object relative clauses in Chinese? Evidence from ERPs[J]. Front Psychol, 2018, 9: 995.
[13] Gerver D.Empirical studies of simultaneous interpretation: a review and a model[M]// Brislin RW. Translation: Applications and Research. New York: Gardiner, 1976: 165-207.
[14] 柳燕梅,江新. 欧美学生汉字学习方法的实验研究—回忆默写法与重复抄写法的比较[J]. 世界汉语教学, 2003(1): 59-67.
[15] Faria A, Race D, Kim K, et al.The eyes reveal uncertainty about object distinctions in semantic variant primary progressive aphasia[J]. Cortex, 2018, 103: 372-381.
[16] Belke E.Long-lasting inhibitory semantic context effects on object naming are necessarily conceptually mediated: Implications for models of lexical-semantic encoding[J]. J Mem Lang, 2013, 69(3): 228-256.
[17] Harvey D Y, Schnur T T.Different loci of semantic interference in picture naming vs. word-picture matching tasks[J]. Front Psychol, 2016, 7: 710.
[18] Weidler B, Abrams R.Simple actions activate semantic associations[J]. Psychon Bull Rev, 2018, 25(4): 1500-1506.
[19] Harvey D Y, Schnur T T.Distinct loci of lexical and semantic access deficits in aphasia: Evidence from voxel-based lesion-symptom mapping and diffusion tensor imaging[J]. Cortex, 2015, 67: 37-58.
[20] Crystal T H, House A S.Articulation rate and the duration of syllables and stress groups in connected speech[J]. J Acoust Soc Am, 1990, 88(1): 101-112.
[21] Obleser J.Re-visiting the electrophysiology of language[J]. Brain Lang, 2015, 148: 23-24.
[22] Payne B, Federmeier K.Contextual constraints on lexico-semantic processing in aging: Evidence from single-word event-related brain potentials[J]. Brain Res, 2018, 1687: 117-128.
[23] Schacht A, Sommer W, Shmuilovich O, et al.Differential task effects on N400 and P600 elicited by semantic and syntactic violations[J]. PLoS One, 2014, 9(3): e91226.
[24] Ren H, Chen X, Qi Z, et al.An ERP study of the processing of epistemic modality adverbs yexu and yiding in mandarin Chinese[J]. Neurosci Lett, 2018,684: 55-60.
[25] Caffarra S, Martin C D. Not all errors are the same: ERP sensitivity to error typicality in foreign accented speech perception [J]. Cortex, 2018, pii: S0010-9452(18)30088-1.
[26] Kutas M, Federmeier K D.Thirty years and counting: finding meaning in the N400 component of the event-related brain potential (ERP)[J]. Annu Rev Psychol, 2011, 62(1): 621-647.
[27] 常静玲,张斌龙,谭中建,等. 基于汉语高频名词下词图匹配语义判断任务的设计与运用范式[J]. 中国康复理论与实践, 2018, 24(8): 917-923.
[28] Coderre E.A semantic priming event-related potential (ERP) task to study lexico-semantic and visuo-semantic processing in autism spectrum disorder[J]. J Vis Exp, 2018(134): e57217.
[29] Blackford T, Holcomb P J, Grainger J, et al.A funny thing happened on the way to articulation: N400 attenuation despite behavioral interference in picture naming[J]. Cognition, 2012, 123(1): 84-99.
[30] Cubelli R, Lotto L, Paolieri D, et al.Grammatical gender is selected in bare noun production: evidence from the picture-word interference paradigm[J]. J Mem Lang, 2005, 53(1): 42-59.
[31] Wang M, Chen Y, Schiller N. Lexico-syntactic features are activated but not selected in bare noun production: Electrophysiological evidence from overt picture naming [J]. Cortex, 2018, pii: S0010-9452(18)30170-9. doi: 10.1016/j.cortex.2018.05.014.
[32] Bentin S, McCarthy G, Wood C C. Event-related potentials, lexical decision and semantic priming[J]. Electroencephalogr Clin Neurophysiol, 1985, 60(4): 343-355.
[33] Rugg M D.The effects of semantic priming and work repetition on event-related potentials[J]. Psychophysiology, 1985, 22(6): 642-647.
[34] Zhu X, Damian M F, Zhang Q.Seriality of semantic and phonological processes during overt speech in Mandarin as revealed by event-related brain potentials[J]. Brain Lang, 2015, 144: 16-25.
[35] Bentin S, Allison T, Puce A, et al.Electrophysiological studies of face perception in humans[J]. J Cogn Neurosci, 1996, 8(6): 551-565.
[36] Itier R J, Taylor M J.Face recognition memory and configural processing: a developmental ERP study using upright, inverted, and contrast-reversed faces[J]. J Cogn Neurosci, 2004, 16(3): 487-502.
[37] Taylor M J, Batty M, Itier R J.The faces of development: a review of early face processing over childhood[J]. J Cogn Neurosci, 2004, 16(8): 1426-1442.
[38] Sysoeva O V, Constantino J N, Anokhin A P.Event-related potential (ERP) correlates of face processing in verbal children with autism spectrum disorders (ASD) and their first-degree relatives: a family study[J]. Mol Autism, 2018, 9(1): 41.
[39] Liu Y, Zhang D, Luo Y.How disgust facilitates avoidance: an ERP study on attention modulation by threats[J]. Soc Cogn Affect Neurosci, 2015, 10(4): 598-604.
[40] Zhang H, Jin Y, Chan J, et al.Dysfunctional early processing of facial expressions in hazardous drinkers: evidence from an ERP study[J]. Sci Rep, 2017, 7(1): 13360.
[41] Neuhaus E, Kresse A, Faja S, et al.Face processing among twins with and without autism: social correlates and twin concordance[J]. Soc Cogn Affect Neurosci, 2016, 11(1): 44-54.
[42] Nickels L.Therapy for naming disorders: Revisiting, revising, and reviewing[J]. Aphasiology, 2002, 16(10-11): 935-979.
[43] Dignam J, Copland D, Rawlings A, et al.The relationship between novel word learning and anomia treatment success in adults with chronic aphasia[J]. Neuropsychologia, 2016, 81: 186-197.
[44] Tuomiranta L, Càmara E, Froudist Walsh S, et al.Hidden word learning capacity through orthography in aphasia[J]. Cortex, 2014, 50: 174-191.
[45] Kim E, Rapcsak S, Andersen S, et al.Multimodal alexia: neuropsychological mechanisms and implications for treatment[J]. Neuropsychologia, 2011, 49(13): 3551-3562.
[46] Lesourd M, Osiurak F, Baumard J, et al.Cerebral correlates of imitation of intransitive gestures: an integrative review of neuroimaging data and brain lesion studies[J]. Neurosci Biobehav Rev, 2018, 95: 44-60.
[47] Zhou R, Hondori H, Khademi M, et al.Predicting gains with visuospatial training after stroke using an EEG Measure of frontoparietal circuit function[J]. Front Neurol, 2018, 9: 597.

工作记忆与词汇学习：基于词图匹配任务的事件相关电位研究

Role of Working Memory in Lexical Access: An Event-related Potential Study Based on Word-picture Matching Tasks

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

Metrics

本文评价

推荐阅读 0

[1]	周治宁, 周容, 肖燕文, 王博文, 吕娇娇, 刘宇. 多靶区经颅直流电刺激对健康成年人工作记忆-姿势控制双任务表现的影响[J]. 《中国康复理论与实践》, 2024, 30(1): 21-28.
[2]	丁妍怡,张胜行,刘雨露,余燕,杨敏光,梁胜祥,柳维林,陶静. 电针对血管性认知障碍大鼠脑功能局部一致性的效果[J]. 《中国康复理论与实践》, 2022, 28(1): 55-61.
[3]	赵静,刘小菠,李涓,郑重,金荣疆. 事件相关电位应用于认知功能研究的可视化分析[J]. 《中国康复理论与实践》, 2022, 28(1): 69-78.
[4]	王贞,张庆苏,胡乃晓,王琦,龚树生. 年龄相关功能性听力下降对记忆功能的影响[J]. 《中国康复理论与实践》, 2020, 26(9): 1093-1096.
[5]	孙晓琴,冯英,肖农. 事件相关电位P300在意识障碍预后评估中的应用进展[J]. 《中国康复理论与实践》, 2020, 26(7): 784-787.
[6]	童禹铭,徐桂芝,郭苗苗,张天恒,王宁. 高频重复经颅磁刺激对大鼠工作记忆局部场电位和锋电位时频特征的影响[J]. 《中国康复理论与实践》, 2020, 26(12): 1401-1409.
[7]	孙伟铭, 董香丽. 工作记忆刷新训练对运动性失语症患者言语流畅性的影响[J]. 《中国康复理论与实践》, 2019, 25(2): 135-139.
[8]	李婧婷, 黄曦妍, 范豪, 李咏雪, 刘鹏, 陈曦. 不同提示策略下帕金森病言语运动调控的机制[J]. 《中国康复理论与实践》, 2018, 24(7): 779-786.
[9]	李泓钰, 王强, 杜晓霞, 王静, 徐舒, 王曼, 宋鲁平. 近红外脑功能成像对卒中后抑郁神经机制的研究[J]. 《中国康复理论与实践》, 2018, 24(4): 427-431.
[10]	毛春燕，孙莉，袁远. 刺激参数对事件相关电位P300 结果的影响①[J]. 《中国康复理论与实践》, 2016, 22(7): 821-823.
[11]	黄幸，韦宇飞，常静玲. 事件相关电位不同内源成分在脑卒中后失语评价中的应用①[J]. 《中国康复理论与实践》, 2016, 22(7): 863-866.
[12]	薛翠萍1,2，恽晓平1,3，张一4，姚球近4，牛秀茹5. 工作记忆训练系统对脑损伤患者工作记忆障碍的疗效①[J]. 《中国康复理论与实践》, 2016, 22(5): 523-527.
[13]	庄妍，庞伟，孙颖，汤敬华. 小组式作业疗法对脑性瘫痪患儿认知功能的影响①[J]. 《中国康复理论与实践》, 2016, 22(4): 455-458.
[14]	李亚梅;徐丽;杨艳;田金艳;余茜. 重复经颅磁刺激对脑梗死后轻度认知功能障碍的影响及安全性研究[J]. 《中国康复理论与实践》, 2015, 21(10): 1128-1132.
[15]	陈正威;张璞;恽晓平;. 工作记忆训练对脑卒中患者大脑功能激活的影响①[J]. 《中国康复理论与实践》, 2015, 21(08): 929-933.