脑卒中认知障碍患者治疗前后的脑电特征

doi:10.3969/j.issn.1006-9771.2020.07.021

《中国康复理论与实践》 ›› 2020, Vol. 26 ›› Issue (7): 847-850.doi: 10.3969/j.issn.1006-9771.2020.07.021

脑卒中认知障碍患者治疗前后的脑电特征

焦磊磊^1,²,孙良文³,高少军³,卢敏³,黄肖群³,石运序¹,季林红²()

1.烟台大学机电汽车工程学院,山东烟台市 264005
2.清华大学摩擦学国家重点实验室智能与生物机械分室,北京市 100084
3.宜昌市第一人民医院康复医学科,湖北宜昌市 443000

收稿日期:2020-02-03 修回日期:2020-03-05 出版日期:2020-07-25 发布日期:2020-07-24
通讯作者: 季林红 E-mail:jilh@tsinghua.edu.cn
作者简介:焦磊磊(1993-),男,汉族,山东禹城市人,硕士研究生,主要研究方向：康复工程、生物机械。|季林红(1962-),男,汉族,北京市人,教授,博士研究生导师,主要研究方向：康复医学工程。

Electroencephalogram for Patients with Post-stroke Cognitive Impairment before and after Treatment

JIAO Lei-lei^1,²,SUN Liang-wen³,GAO Shao-jun³,LU Min³,HUANG Xiao-qun³,SHI Yun-xu¹,JI Lin-hong²()

1. School of Mechanical and Electronic Engineering & Automobile Engineering, Yantai University, Yantai, Shandong 264005, China
2. Department of Precision Instruments and Mechanology, Tsinghua University, Beijing 100084, China
3. Department of Rehabilitation Medicine, Yichang First People's Hospital, Yichang, Hubei 443000, China

Received:2020-02-03 Revised:2020-03-05 Published:2020-07-25 Online:2020-07-24
Contact: JI Lin-hong E-mail:jilh@tsinghua.edu.cn

摘要/Abstract

摘要：

目的分析卒中后认知障碍(PSCI)患者治疗前后的脑电图变化。方法 2018年10月至2019年4月,12例PSCI患者在完成常规认知训练和重复经颅磁刺激治疗6周前后,采用简易精神状态检查、蒙特利尔认知评估量表和改良Barthel指数进行评定,闭眼静息态下采集脑电图。结果治疗后,患者各项评分均明显改善(|t| > 3.507, P < 0.01)。α波绝对功率和相对功率增高(| t| > 2.522, P < 0.05),脑对称指数和DTABR降低( t > 2.435, P < 0.05)。结论 PSCI患者脑电图随认知功能恢复发生相应改变,可进一步研究脑电图与认知功能的关系。

关键词: 脑卒中, 认知, 脑电图, 评定

Abstract:

Objective To analyze the changes of electroencephalogram (EEG) before and after treatment in patients with post-stroke cognitive impairment (PSCI). Methods From October, 2018 to April, 2019, twelve PSCI patients received cognitive training and repetitive transcranial magnetic stimulation for six weeks. They were assessed with Mini-Mental State Examination, Montreal Cognitive Assessment and modified Barthel Index before and after treatment, while their closed-eye resting EEG were collected. Results The scores of all the assessments improved after treatment (|t| > 3.507, P < 0.01); while alpha absolute power and alpha relative power increased (| t| > 2.522, P < 0.05), and brain symmetry index and DTABR decreased ( t > 2.435, P < 0.05). Conclusion The characteristics of EEG of PSCI patients changes with the recovery of cognitive function. Further research is needed about the relationship between EEG and cognitive function.

Key words: stroke, cognition, electroencephalogram, assessment

中图分类号:

R743.3

焦磊磊,孙良文,高少军,卢敏,黄肖群,石运序,季林红. 脑卒中认知障碍患者治疗前后的脑电特征[J]. 《中国康复理论与实践》, 2020, 26(7): 847-850.

JIAO Lei-lei,SUN Liang-wen,GAO Shao-jun,LU Min,HUANG Xiao-qun,SHI Yun-xu,JI Lin-hong. Electroencephalogram for Patients with Post-stroke Cognitive Impairment before and after Treatment[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2020, 26(7): 847-850.

图/表 2

参考文献 29

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时间	n	MMSE	MoCA	MBI
治疗前	12	20.25±5.83	15.92±5.81	54.16±20.32
治疗后	12	24.08±6.50	19.33±5.68	67.08±22.20
t值		3.507	3.832	4.531
P值		0.005	0.003	0.001

时间	n	αAP(μV²)	αRP	BSI	DTABR
治疗前	12	7.21±3.76	0.09±0.04	0.61±0.14	4.11±3.25
治疗后	12	10.28±6.55	0.13±0.05	0.52±0.09	2.27±1.58
t值		-2.522	-2.866	3.15	2.435
P值		0.028	0.015	0.009	0.033

脑卒中认知障碍患者治疗前后的脑电特征

Electroencephalogram for Patients with Post-stroke Cognitive Impairment before and after Treatment

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