肢体协调训练对早期原发性帕金森病患者肺功能的效果

doi:10.3969/j.issn.1006-9771.2022.08.012

摘要/Abstract

摘要：

目的观察肢体协调训练对早期原发性帕金森患者肺功能的效果。

方法 2021年2月至2022年2月,本院原发性帕金森患者60例根据治疗方案分为对照组(n = 30)和试验组(n = 30),分别接受常规药物治疗和常规药物联合肢体协调训练治疗,共12周。治疗前后,采用肺功能仪测量患者第1秒用力呼气容积(FEV₁)、用力肺活量(FVC)、最大呼气流量(PEF)和肺活量(VC),采用心肺运动试验(CPET)测量峰值摄氧量(VO_2peak)、无氧阈(AT)、峰值功率(WR_peak),采用呼吸驱动仪测量最大吸气压(MIP)和最大呼气压(MEP)。

结果治疗后,试验组FEV₁、FVC、PEF、VC、VO_2peak、AT、WR_peak、MIP、MEP均提高(t > 2.087, P < 0.05),且均优于对照组(t > 2.079, P < 0.05)。

结论肢体协调训练可改善早期原发性帕金森患者肺功能,提高有氧运动能力,增强呼吸肌肌力。

关键词: 早期原发性帕金森病, 肢体协调训练, 肺功能

Abstract:

Objective To observe the effect of interlimb-coordinated training on pulmonary function in patients with early primary Parkinson's disease.

Methods From February, 2021 to February, 2022, 60 patients with primary Parkinson's disease in Affiliated Hospital of Southwest Medical University were divided into control group (n = 30) and experimental group (n = 30) according to the management, who accepted medicine and medicine combined with interlimb-coordinated training, for twelve weeks, respectively. Before and after treatment, the forced expiratory volume in the first second (FEV₁), forced vital capacity (FVC), maximum expiratory flow (PEF) and vital capacity (VC) were measured with pulmonary function instrument, while the peak oxygen uptake (VO_2peak), anaerobic threshold (AT) and peak power (WR_peak) were measured with Cardiopulmonary Exercise Test (CPET), and the maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) were measured with respiratory driving instrument.

Results After treatment, FEV₁, FVC, PEF, VC, VO_2peak, AT, WR_peak, MIP and MEP increased in the experimental group (t > 2.087, P< 0.05), and they were more in the experimental group than in the control group (t > 2.079, P< 0.05).

Conclusion Interlimb-coordinated training could improve the pulmonary function, aerobic exercise ability and respiratory muscle strength of patients with early primary Parkinson's disease.

Key words: early primary Parkinson's disease, interlimb-coordinated training, pulmonary function

中图分类号:

R742.5

王洁萍,彭娟,张斐雪,樊必双,胥方元. 肢体协调训练对早期原发性帕金森病患者肺功能的效果[J]. 《中国康复理论与实践》, 2022, 28(8): 966-971.

WANG Jieping,PENG Juan,ZHANG Feixue,FAN Bishuang,XU Fangyuan. Effect of interlimb-coordinated training on pulmonary function in patients with early primary Parkinson's disease[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2022, 28(8): 966-971.

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组别	n	性别(男/女)/n	年龄/岁	病程/年
对照组	30	13/17	63.25±2.47	3.26±1.89
试验组	30	15/15	61.98±3.71	3.15±2.03
χ²/t值		42.576	41.271	1.863
P值		0.063	0.069	0.078

组别	n	治疗前	治疗后	t值	P值
对照组	30	2.09±0.53	2.21±0.67	2.089	0.045
试验组	30	2.11±0.58	2.63±0.84	2.217	0.030
t值		1.836	2.153
P值		0.061	0.037

组别	n	治疗前	治疗后	t值	P值
对照组	30	2.78±0.49	2.84±0.71	2.031	0.058
试验组	30	2.93±0.65	3.24±0.73	2.087	0.046
t值		2.025	2.091
P值		0.053	0.043

组别	n	治疗前	治疗后	t值	P值
对照组	30	252.12±10.32	262.41±9.48	2.103	0.039
试验组	30	251.06±11.05	318.39±13.72	2.365	0.013
t值		1.918	2.307
P值		0.073	0.019

组别	n	治疗前	治疗后	t值	P值
对照组	30	3.09±0.23	3.11±0.17	1.854	0.063
试验组	30	3.01±0.25	3.94±0.31	2.093	0.041
t值		1.986	2.079
P值		0.055	0.047