下肢截肢患者运动表象的脑电功率谱改变

doi:10.3969/j.issn.1006-9771.2022.11.017

《中国康复理论与实践》 ›› 2022, Vol. 28 ›› Issue (11): 1360-1364.doi: 10.3969/j.issn.1006-9771.2022.11.017

• 辅助技术 • 上一篇

下肢截肢患者运动表象的脑电功率谱改变

单新颖^1,²,俞梦孙^1,³()

1.北京航空航天大学生物与医学工程学院，北京市 100191
2.国家康复辅具研究中心，老年功能障碍康复辅助技术北京市重点实验室，北京市 100176
3.空军特色医学中心，北京市 100142

收稿日期:2021-10-25 修回日期:2022-04-29 出版日期:2022-11-25 发布日期:2022-12-20
通讯作者: 俞梦孙 E-mail:biomed_engi@163.com
作者简介:单新颖(1983-)，男，汉族，江西九江市人，博士，高级工程师，主要研究方向：康复工程、脑电信号分析。
基金资助:
国家重点研发计划课题(2020YFC2005801)

Electroencephalogram power spectrum as motor imagery for lower limb amputees

SHAN Xinying^1,²,YU Mengsun^1,³()

1. School of Biological Science and Medical Engineering, Beihang University, Beijng 100191, China
2. Beijing Key Laboratory of Rehabilitation Technical Aids for Old-Age Disability, National Research Center for Rehabilitation Technical Aids, Beijing 100176, China
3. Air Force Medical Center PLA, Beijing 100142, China

Received:2021-10-25 Revised:2022-04-29 Published:2022-11-25 Online:2022-12-20
Contact: YU Mengsun E-mail:biomed_engi@163.com
Supported by:
National Key Research and Development Program(2020YFC2005801)

摘要/Abstract

摘要：

目的探索下肢截肢后大脑可塑性变化机制，揭示下肢截肢后运动表象相关电极的能量变化。

方法 2021年4月至10月，选取下肢截肢患者21例和健康人18例进行运动表象任务，同步记录256导脑电图，分析C3和C4电极α(8~13 Hz)和β(13~30 Hz)频段的功率谱。

结果在β频段内，在表象左、右腿运动和左脚运动时，患者C4点功率高于健康人(P < 0.05)。

结论下肢截肢患者表象运动任务时有脑电功率改变，可能与幻肢痛和大脑可塑性相关。

关键词: 下肢截肢, 运动表象, 脑电图, 功率谱分析, 大脑可塑性

Abstract:

Objective To explore the mechanism of brain plasticity after lower limb amputation, and the electroencephalogram (EEG) energy changes during motor imagery.

Methods From April to October, 2021, 21 lower limb amputees and 18 healthy subjects were selected to perform motor imagery task, while the 256-EEG were recorded synchronously. The power spectrum of EEG at C3 and C4 electrodes in α (8~13 Hz) and β (13~30 Hz) frequency bands were compared.

Results The power of C4 electrode in β frequency band was stronger in the amputees than in the healthy subjects as imagery of movements of left and right legs, and left foot.

Conclusion EEG power increases in the amputees as motor imagery, which may relate to phantom limb pain and brain plasticity after amputation.

Key words: lower limb amputation, motor imagery, electroencephalogram, power spectrum analysis, brain plasticity

中图分类号:

R496

单新颖,俞梦孙. 下肢截肢患者运动表象的脑电功率谱改变[J]. 《中国康复理论与实践》, 2022, 28(11): 1360-1364.

SHAN Xinying,YU Mengsun. Electroencephalogram power spectrum as motor imagery for lower limb amputees[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2022, 28(11): 1360-1364.

图/表 3

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参考文献 37

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特征	n	性别(男/女)/n	年龄/岁	受教育程度/年	截肢时间/月	幻肢痛评分
对照组	18	16/2	46.00±10.14	8.83±0.71
左下肢截肢	11	10/1	56.45±7.57	8.73±0.47	13.55±7.86	2.09±1.70
右下肢截肢	10	9/1	48.80±14.70	8.60±0.70	17.00±13.75	1.80±1.23
χ²/F/t值		0.031	3.077	0.423	-0.715	0.445
P值		0.985	0.058	0.659	0.483	0.661

电极	表象部位	对照组(n = 18)	左下肢截肢(n = 11)	右下肢截肢(n = 10)	F值	P值
C3	左腿	0.046±0.023	0.044±0.030	0.060±0.028	1.646	0.207
C3	右腿	0.046±0.025	0.047±0.012	0.058±0.025	1.000	0.378
	左脚	0.081±0.045	0.090±0.033	0.104±0.050	0.921	0.407
	右脚	0.086±0.047	0.090±0.039	0.106±0.051	0.615	0.546
C4	左腿	0.046±0.030	0.046±0.016	0.059±0.029	0.953	0.395
C4	右腿	0.046±0.032	0.048±0.017	0.059±0.027	0.713	0.497
	左脚	0.074±0.042	0.074±0.018	0.100±0.047	1.766	0.185
	右脚	0.076±0.037	0.077±0.016	0.101±0.044	1.929	0.160

电极	表象部位	对照组(n = 18)	左下肢截肢(n = 11)	右下肢截肢(n = 10)	F值	P值
C3	左腿	0.024±0.085	0.033±0.024	0.040±0.023	2.626	0.086
C3	右腿	0.024±0.078	0.035±0.029	0.039±0.022	2.075	0.140
	左脚	0.041±0.016	0.066±0.081	0.074±0.057	1.550	0.226
	右脚	0.042±0.015	0.063±0.078	0.070±0.045	1.299	0.285
C4	左腿	0.022±0.087	0.030±0.015	0.036±0.012	4.328	0.021
C4	右腿	0.023±0.009	0.031±0.017	0.035±0.011	3.620	0.037
	左脚	0.036±0.012	0.054±0.041	0.061±0.015	3.771	0.033
	右脚	0.039±0.013	0.052±0.038	0.059±0.015	2.763	0.077

下肢截肢患者运动表象的脑电功率谱改变

Electroencephalogram power spectrum as motor imagery for lower limb amputees

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