在线和离线高精度经颅直流电刺激对健康成年人手指运动技能学习效果的随机对照试验

doi:10.3969/j.issn.1006-9771.2024.08.011

《中国康复理论与实践》 ›› 2024, Vol. 30 ›› Issue (8): 957-964.doi: 10.3969/j.issn.1006-9771.2024.08.011

在线和离线高精度经颅直流电刺激对健康成年人手指运动技能学习效果的随机对照试验

牛茂林¹, 赵潭¹, 刘晓丽², 郭峰¹()

1.沈阳体育学院运动健康学院，辽宁沈阳市 110102
2.沈阳体育学院附属竞技体育学校，辽宁沈阳市 110102

收稿日期:2024-05-14 修回日期:2024-06-21 出版日期:2024-08-25 发布日期:2024-09-11
通讯作者: 郭峰，男，教授，主要研究方向：运动控制与脑研究。 E-mail： guofeng_first@163.com
作者简介:牛茂林(1998-)，男，汉族，山东桓台县人，硕士，治疗师，主要研究方向：运动与脑功能研究。
基金资助:
辽宁省教育厅基本科研项目重点项目(JYTZD2023133);辽宁省自然科学基金面上项目(2022-MS-415)

Effect of online and offline high definition transcranial direct current stimulation on finger motor skill learning in healthy adults: a randomized controlled trial

NIU Maolin¹, ZHAO Tan¹, LIU Xiaoli², GUO Feng¹()

1. College of Exercise and Health, Shenyang Sport University, Shenyang, Liaoning 110102, China
2. Affiliated Competitive Sports School, Shenyang Sport University, Shenyang, Liaoning 110102, China

Received:2024-05-14 Revised:2024-06-21 Published:2024-08-25 Online:2024-09-11
Supported by:
Educational Department of Liaoning Basic Scientific Research Program (Key)(JYTZD2023133);Liaoning Natural Science Foundation (General)(2022-MS-415)

摘要/Abstract

摘要：

目的观察高精度经颅直流电刺激(HD-tDCS)不同刺激时机(在线刺激、离线刺激)对健康成年人手指运动技能学习效果的影响。

方法 2022年3月至11月，在沈阳体育学院招募右利手男性受试者31例，随机分为3组。分别在HD-tDCS在线刺激、离线刺激以及假刺激下，完成顺序视觉等距捏力任务学习，共3 d。观察每天运动技能学习量、运动技能学习总量和速度-精度函数(SAF)。

结果各组运动技能学习量均增加，在线刺激组增加最多(F = 24.692, P < 0.001)，且第3天时，显著高于离线刺激组(t = 4.732, P < 0.001)和假刺激组(t = 3.839, P = 0.004)。运动技能学习总量：在线刺激组 = 离线刺激组 > 假刺激组。在线刺激组SAF高于离线刺激组和假刺激组。

结论 HD-tDCS刺激可提高健康受试者手指运动技能学习效果，在线刺激效果最佳。

关键词: 重复高精度经颅直流电刺激, 在线刺激, 离线刺激, 运动技能学习, 随机对照试验

Abstract:

Objective To investigate the effect of high definition transcranial direct current stimulation (HD-tDCS) at different stimulation timings (online and offline) on finger motor skill learning in healthy adults.

Methods From March to November, 2022, 31 right-handed male participants were recruited from Shenyang Sport University and randomly assigned to three groups, who received online, offline or sham HD-tDCS respectively during the three-day sequential visual isometric pinch task learning process. The daily motor skill learning gains, total motor skill learning gains and speed-accuracy function (SAF) were observed.

Results The daily motor skill learning gains increased in all the groups, and it was the best in the online group (F = 24.692, P < 0.001); the learning gains were better in the online group than in the offline group (t = 4.732, P < 0.001) and the sham group (t = 3.839, P = 0.004) on the third day. The total motor skill learning gains were ranked as the online group = the offline group > the sham group. SAF data indicated that the online group outperformed both the offline and sham groups.

Conclusions HD-tDCS can promote the finger motor skill learning in healthy adults, and online HD-tDCS is more effective.

Key words: repetitive high definition transcranial direct current stimulation, online stimulation, offline stimulation, motor skill learning, randomized controlled trial

中图分类号:

R804.23

牛茂林, 赵潭, 刘晓丽, 郭峰. 在线和离线高精度经颅直流电刺激对健康成年人手指运动技能学习效果的随机对照试验[J]. 《中国康复理论与实践》, 2024, 30(8): 957-964.

NIU Maolin, ZHAO Tan, LIU Xiaoli, GUO Feng. Effect of online and offline high definition transcranial direct current stimulation on finger motor skill learning in healthy adults: a randomized controlled trial[J]. Chinese Journal of Rehabilitation Theory and Practice, 2024, 30(8): 957-964.

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组别	n	年龄/岁	身高/cm	体质量/kg	体质量指数/(kg•m^-2)
假刺激组	11	22.6±1.3	174.6±2.8	74.9±5.4	24.5±2.2
离线刺激组	11	22.3±1.2	176.0±4.1	78.0±5.3	25.2±2.3
在线刺激组	9	22.6±1.0	177.6±3.1	74.6±4.3	23.6±1.1
F值		0.191	1.970	1.476	1.537
P值		0.828	0.158	0.246	0.233

组别	n	头痛	瘙痒	麻刺	烧灼
假刺激组	11	3	5	3	4
离线刺激组	11	3	3	4	5
在线刺激组	9	2	4	5	3
χ²值		0.085	0.942	1.708	0.346
P值		0.958	0.624	0.426	0.841

组别	n	第1天	第2天	第3天
假刺激组	11	-1.947±0.372	-0.758±0.374	-0.503±0.213
离线刺激组	11	-2.080±0.939	-0.983±0.340	-0.790±0.332
在线刺激组	9	-2.133±1.068	-0.785±0.409	0.064±0.291

效应	平方和	自由度	均方	F值	P值	η_p²值
组别	0.345	2	0.173	0.910	0.424	0.108
时间	26.158	2	13.079	39.743	< 0.001	0.851
组别×时间	1.535	4	0.384	5.101	0.020	0.405

组别	时间	时间	平均值差	P值	95%CI
组别	时间	时间	平均值差	P值	上限	下限
在线刺激组	第1天	第2天	-1.348	< 0.001	-1.894	-0.802
	第1天	第3天	-2.198	< 0.001	-2.856	-1.540
	第2天	第3天	-0.850	< 0.001	-1.198	-0.502
离线刺激组	第1天	第2天	-1.098	0.001	-1.644	-0.552
	第1天	第3天	-1.290	0.001	-1.948	-0.632
	第2天	第3天	-0.192	0.258	-0.539	0.156
假刺激组	第1天	第2天	-1.188	< 0.001	-1.734	-0.642
	第1天	第3天	-1.445	< 0.001	-2.103	-0.787
	第2天	第3天	-0.257	0.137	-0.604	0.091

在线和离线高精度经颅直流电刺激对健康成年人手指运动技能学习效果的随机对照试验

Effect of online and offline high definition transcranial direct current stimulation on finger motor skill learning in healthy adults: a randomized controlled trial

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组别	n	运动技能学习总量
假刺激组	11	1.74±1.40
离线刺激组	11	3.15±1.50
在线刺激组	9	4.15±1.36

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