目的探讨中文版约翰霍普金斯改良认知评价量表(ACE)在神经系统重症监护室(NICU)患者认知功能评定中的有效性。方法选择2014 年5 月~2015 年6 月入住NICU的94 例患者(NICU 组)和52 名健康体检人(对照组)，分别采用中文版ACE及简易精神状态检查(MMSE)进行测评。结果ACE总分与MMSE总分呈高度相关(r=0.805, P<0.001)。NICU 组和对照组间，ACE和MMSE 各项评分和总分均有显著性差异(t>2.458, P<0.05)。受试者操作曲线曲线下面积ACE 为(0.669±0.046)，MMSE 为(0.713±0.048)，无显著性差异(Z=0.707, P=0.480)。结论中文版ACE可以作为NICU患者认知障碍筛查的工具。

Objective To investigate the clinical validity of the Chinese version of John Hopkins Adapted Cognitive Exam (ACE) for inpatients in neurological intensive care unit (NICU). Methods From May, 2014 to June, 2015, 94 inpatients in NICU and 52 healthy persons were assessed with the Chinese version of ACE and Mini-Mental State Examination (MMSE). Results The total score of ACE correlated with the total score of MMSE (r=0.805, P<0.001). There was a significant difference in the total score and the scores of the subtests of both the ACE and MMSE between the patients and the controls (t>2.458, P<0.05). The area under the receiver operating curve was not different between ACE and MMSE (Z=0.707, P=0.480). Conclusion The Chinese version of ACE can be the tool for assessment of cognition for patients in NICU.