目的观察POEMS综合征后遗症期的康复疗效。方法对2 例以多发性周围神经损伤为主要表现的POEMS综合征患者，进行物理疗法、作业疗法、针灸、表面肌电生物反馈等综合康复治疗。结果康复治疗后患者肌力、躯干平衡、站立平衡能力、日常生活活动能力有所提高。其中，第1 例患者Berg 平衡量表得分由18 分增加到28 分，第2 例患者改良Bathel 指数由55 分提高到70 分。结论综合康复治疗可改善POEMS综合征后遗症期患者的功能，表面肌电生物反馈在POEMS综合征后遗症期的康复治疗中起重要作用。

Objective To observe the effect of comprehensive rehabilitation on POEMS syndrome during sequel period. Methods Two cases of POEMS syndrome with multiple peripheral nerve injury as the main manifestation received physical therapy, occupational therapy, acupuncture, surface electromyography biofeedback and other comprehensive rehabilitation treatment. Results After treatment, the muscle strength, trunk balance, standing balance ability, activities of daily living (ADL) improved. The score of Berg Balance Scale increased from 18 to 28 in the first case, the modified Bathel Index increased from 55 to 70 in the second case. Conclusion Comprehensive rehabilitation can improve the function of patients with POEMS syndrome during sequel period, and surface electromyography biofeedback plays an important role.