目的 观察脉冲射频治疗难治性眶下神经痛患者的效果。方法 2012年1月至2014年12月，对49例药物和神经阻滞治疗无效的难治性眶下神经痛患者行脉冲射频治疗。记录术后1 d、1周、2周、1个月、3个月、6个月、1年和2年时的疼痛数字评分(NRS)，以治疗后患者NRS=0或NRS降低50%以上为标准计算有效率，并记录卡马西平用量及副作用。结果 术后1个月、3个月、6个月、1年及2年时有效率分别为67%、67%、65%、59%及51%。除8例(16%)患者脉冲射频术后出现短暂(1个月内)轻微麻木感外无其他严重副作用。结论 脉冲射频治疗难治性眶下神经痛患者安全、有效，有望成为保守治疗无效患者的一种治疗选择。
Objective To observe the effect of pulsed radiofrequency (PRF) on refractory infraorbital neuralgia. Methods From January, 2012 to December, 2014, 49 patients who received ineffective conservative therapy including medicine and nerve blockade underwent PRF treatment. Postoperative Numeric Rating Scale (NRS)=0 or 50% diminution of NRS was considered effective. NRS, effective rate, additional carbamazepine dosage and side effects were recorded on the first day, the first week, the second week, the first month, the third month, the sixth month, the first year, and the second year after operation. Results The effective rate were 67%, 67%, 65%, 59% and 51% on the first month, the third month, the sixth month, the first year, and the second year after operation, respectively. No serious side effect was observed, except that eight patients felt short-term (within one month) mild numbness. Conclusion PRF technique is safe and effective for refractory infraorbital neuralgia, and may become an alternative therapy.
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