综述

老年认知功能障碍患者默认网络、凸显网络和中央执行网络研究进展

  • 王金芳 ,
  • 陈红燕 ,
  • 李越秀 ,
  • 叶娜 ,
  • 冯丽 ,
  • 王诗男 ,
  • 张玉梅
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  • 1.首都医科大学附属北京天坛医院神经病学中心血管神经病学科,国家神经系统疾病临床医学研究中心,北京脑重大疾病研究院脑卒中研究所,脑血管病转化医学北京市重点实验室,北京市 100050;
    2.长江航运总医院,武汉脑科医院神经内科,湖北武汉市 430015;
    3.首都医科大学附属北京天坛医院影像科,北京市 100050
王金芳(1984-),女,汉族,河南卫辉市人,博士研究生,主治医师,主要研究方向:脑血管病与认知功能障碍。通讯作者:张玉梅,博士研究生导师,主要研究方向:脑血管病、认知障碍。

收稿日期: 2017-11-20

  修回日期: 2018-01-11

  网络出版日期: 2018-03-27

基金资助

1.国家自然科学基金项目(No. 81371201); 2.首都医科大学基础与临床合作重点项目(No. 16JL03); 3.北京市医院管理局临床技术创新项目(No. ZYLX201836); 4.湖北省卫生计生委科研项目(No. WJ2017F057)

Advance in Default Mode Network, Salience Network and Central Executive Network about Cognitive Function in Old Persons (review)

  • WANG Jin-fang ,
  • CHEN Hong-yan ,
  • LI Yue-xiu ,
  • YE Na ,
  • FENG Li ,
  • WANG Shi-nan ,
  • ZHANG Yu-mei
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  • 1. Department of Neurology, Beijing Tiantan Hospital, Capital Medical University; China National Clinical Research Center for Neurological Diseases; Center of Stroke, Beijing Institute for Brain Disorders; Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing 100050, China;
    2. Department of Neurology, General Hospital of the Yangtze River Shipping, Wuhan Brain Hospital, Wuhan, Hubei 430015, China;
    3. Department of Neuroimaging, Beijing Neurosurgery Institute, Capital Medical University, Beijing 100050, China

Received date: 2017-11-20

  Revised date: 2018-01-11

  Online published: 2018-03-27

Supported by

Supported by National Natural Science Foundation of China (No. 81371201), Capital Medical University Research Project for Basic and Clinical Cooperation (Key) (No. 16JL03), Beijing Municipal Administration of Hospitals Special Funding for Clinical Medicine Development (No. ZYLX201836) and Hubei Health and Family Planning Committee Research Project (No. WJ2017F057)

摘要

健康老年人及老年认知功能障碍患者默认网络、凸显网络和中央执行网络的功能连接发生改变,且不同程度认知功能障碍患者表现出不同的改变模式。利用静息态功能磁共振技术对痴呆早期患者脑内在网络的连接变化进行监测具有重要意义。

本文引用格式

王金芳 , 陈红燕 , 李越秀 , 叶娜 , 冯丽 , 王诗男 , 张玉梅 . 老年认知功能障碍患者默认网络、凸显网络和中央执行网络研究进展[J]. 中国康复理论与实践, 2018 , 24(3) : 282 -286 . DOI: 10.3969/j.issn.1006-9771.2018.03.006

Abstract

A lot of researches indicate the relationship between cognitive impairment and functional connectivity of default mode network, salience network and central executive network. The changes of networks are various in different cognitive dysfunction. It is important to apply resting state functional magnetic resonance in the old adults with cognitive dysfunction.

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