专题

经颅直流电刺激治疗帕金森病认知障碍的研究进展

  • 顾彬 ,
  • 王强 ,
  • 雷幸幸 ,
  • 宋鲁平
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  • 1.首都医科大学康复医学院,北京市 100068;
    2.中国康复研究中心北京博爱医院,北京市 100068;
    3.神经损伤与康复北京市重点实验室,北京市 100068
顾彬(1986-),男,汉族,山东滨州市人,硕士研究生,治疗师,主要研究方向:神经康复、认知神经科学、作业治疗。通讯作者:宋鲁平(1964-),女,汉族,山东人,主任医师、教授,博士研究生导师,主要研究方向:神经康复、认知神经科学。

收稿日期: 2018-05-21

  修回日期: 2018-06-22

  网络出版日期: 2018-08-01

基金资助

1.国家重点研发计划(No. 2016YFF0201002); 2.中央级公益性科研院所基本科研业务费专项资金项目(No. 2016CZ-6)

Advance in Transcranial Direct Current Stimulation for Cognitive Impairment in Parkinson's Disease (review)

  • GU Bin ,
  • WANG Qiang ,
  • LEI Xing-xing ,
  • SONG Lu-ping
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  • 1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China;
    2. Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China;
    3. Beijing Key Laboratory of Neural Injury and Rehabilitation, Beijing 100068, China

Received date: 2018-05-21

  Revised date: 2018-06-22

  Online published: 2018-08-01

摘要

认知障碍是帕金森病最常见的非运动症状,可能与神经递质改变、皮质萎缩、异常蛋白沉积等有关,严重影响患者运动功能和日常生活活动能力。经颅直流电刺激可改变皮质兴奋性、影响脑区局部血流量、改变突触性能,开始应用于帕金森病认知障碍的康复治疗。

本文引用格式

顾彬 , 王强 , 雷幸幸 , 宋鲁平 . 经颅直流电刺激治疗帕金森病认知障碍的研究进展[J]. 中国康复理论与实践, 2018 , 24(7) : 773 -778 . DOI: 10.3969/j.issn.1006-9771.2018.07.005

Abstract

Cognitive impairment is the most common non-motor symptom of Parkinson's disease (PD), which may associate with the disorders of transmitters, cortical atrophy, proteinosis, etc., and seriously influence the motor function, ability of daily life of the patients. Transcranial direct current stimulation (tDCS), which may adjust the cerebral excitability, regional blood flow, plasticity of synapses, etc., has been used for PD cognitive impairment.

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