目的 观察健身气功八段锦对轻度认知障碍(MCI)患者认知水平的影响。方法 2016年1月至6月,社区MCI患者60例随机分为对照组(n=30)和练功组(n=30),练功组予八段锦干预6个月,对照组无干预。干预前后分别采用蒙特利尔认知评估量表(MoCA)进行评估;检测血脂,血清白细胞介素-6 (IL-6)、乙酰胆碱(Ach)、超氧化物歧化酶(SOD)和丙二醛(MDA)水平。结果 6个月后,练功组MoCA总分及视空间与执行功能、抽象思维和延迟回忆评分明显高于对照组(t>3.576, P<0.01)。练功组血清总胆固醇、IL-6和MDA水平低于对照组(t>2.744, P<0.05),高密度脂蛋白胆固醇、Ach和SOD水平明显高于对照组(t>2.922, P<0.01)。结论 健身气功八段锦能改善MCI患者的认知功能,且有降血脂、抗氧化和抗炎作用,两者之间可能有关。
Objective To observe the effect of Baduanjin on mild cognitive impairment (MCI). Methods From January to June, 2016, 60 patients with MCI in community were randomly divided into control group (n=30) and training group (n=30). The training group accepted training of Baduanjin for six months, and the control group accepted no intervention. They were assessed with Montreal Cognitive Assessment (MoCA) before and after intervention; while the blood lipid, and serum interleukin-6 (IL-6), acetylcholine (Ach), superoxide dismutase (SOD) and malondialdehyde (MDA) were detected. Results The total score, and scores of visual space and executive function, abstract and delayed memory of MoCA were more in the training group than in the control group after intervention (t>3.576, P<0.01), while the level of total cholesterol, IL-6 and MDA decreased (t>2.744, P<0.05), and the level of high density lipoprotein cholesterol, Ach and SOD increased (t>2.922, P<0.01). Conclusion Baduanjin can improve the cognitive function in MCI patients, as well as reducing blood fat, oxidation and inflammation. There may be some relationship between them.
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