《中国康复理论与实践》

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正常人简单与复杂乘法运算的功能磁共振成像研究①

张璞,恽晓平   

  1. 1.首都医科大学康复医学院,北京市100068;2.中国康复研究中心北京博爱医院康复评定科,北京市100068。
  • 出版日期:2016-05-25 发布日期:2016-07-04

Brain Activation in Simple or Complex Multiplication Tasks in Normal Subjects: A Functional Magnetic Resonance Imaging Study

ZHANG Pu, YUN Xiao-ping   

  • Published:2016-05-25 Online:2016-07-04

摘要: 目的探讨正常人完成简单与复杂乘法运算任务时的脑功能激活特征。方法2010 年6 月~2012 年6 月,采用任务态功能磁共振成像(fMRI),观察13 名正常人完成对照任务、视空间记忆、简单(一位数)乘法和复杂(二或三位数)乘法4 种任务下激活的脑区。结果相较于对照任务,视空间记忆任务主要激活双侧枕叶、右侧楔前叶、右侧顶上小叶;简单乘法任务主要激活双侧枕中回、左侧顶上小叶、左侧扣带回、左侧额中回以及左侧额下回;复杂乘法任务主要激活右侧顶上小叶、右侧额下回和双侧额中回。结论复杂乘法运算的正确执行依赖于一个右侧顶-额叶网络,该网络支持计算过程空间布局信息的存储。

关键词: 乘法, 单位数, 多位数, 运算, 功能磁共振成像

Abstract: Objective To explore the characteristics of brain activation when solving simple multiplication and complex multiplication tasks. Methods From June, 2010 to June, 2012, Thirteen normal subjects completed four functional magnetic resonance imaging (fMRI) experiments, including control tasks, visuospatial memory tasks, simple (single-digit) multiplication tasks and complex (multi-digit) multiplication tasks. Results Compared with the control tasks, visuospatial memory tasks activated the bilateral occipital lobe, the right precuneus and superior parietal lobe; simple multiplication tasks activated the bilateral middle occipital gyri, the left superior parietal lobe, the left cingulate gyrus, the left middle frontal gyrus and inferior frontal gyrus; complex multiplication tasks activated the right superior parietal lobe, the right inferior frontal gyrus, and the bilateral middle frontal gyri. Conclusion A right parieto-frontal network is involved in the multi-digit multiplication, which supports the containing of the spatial layout information.

Key words: multiplication, single-digit, multi-digit, arithmetic, functional magnetic resonance imaging