《中国康复理论与实践》

《中国康复理论与实践》

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事件相关电位不同内源成分在脑卒中后失语评价中的应用①

黄幸，韦宇飞，常静玲   

  1. 北京中医药大学东直门医院神经内科，北京市100700。
  • 出版日期:2016-07-25 发布日期:2016-09-22

Endogenous Components of Event-related Potential Used in Evaluation for Post-stroke Aphasia

HUANG Xing, WEI Yu-fei, CHANG Jing-ling   

  1. Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
  • Published:2016-07-25 Online:2016-09-22

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摘要： 失语症是脑卒中后主要并发症之一，选用有效的评价方法具有重大意义。事件相关电位(ERP)已成为国内外神经科学的研究热点，其中P300、N400、失匹配负波(MMN)、关联性负变(CNV)作为ERP的内源成分，已广泛运用于大脑功能损害的临床诊断和评定，在语言功能评价方面的优势日渐凸显。本文论述ERP 的不同内源成分在脑卒中后失语中的应用，并着重分析比较N400 和P300。

关键词: 脑卒中, 失语症, 事件相关电位, 内源成分, 评价

Abstract: Aphasia is one of the major complications after stroke, which needs an effective assessment. Event-related potential (ERP) has been widely researched in neurology, the endogenous components, such as P300, N400, mismatch negativity (MMN), contingent negative variation (CNV) have been widely used in diagnosis and evaluation of the impairment of brain function, including the language function. This paper discussed the application of different endogenous components of ERP in aphasia after stroke, especially the comparative analysis of N400 and P300.

Key words: stroke, aphasia, event-related potential, endogenous components, assessment