《中国康复理论与实践》

《中国康复理论与实践》

• 临床研究 • 上一篇    下一篇

115 例脊髓损伤患者血栓预防情况分析①

卫波，周红俊，刘根林，王一吉，郑樱，张缨，郝春霞，康海琼，逯晓蕾，袁媛   

  1. 1. 首都医科大学康复医学院，北京市100068；2. 中国康复研究中心北京博爱医院脊髓损伤康复科，北京市100068。
  • 出版日期:2016-08-25 发布日期:2016-09-22

Retrospective Analysis of Thromboembolism Prophylaxis in 115 Patients with Spinal Cord Injury

WEI Bo, ZHOU Hong- jun, LIU Gen- lin, WANG Yi- ji, ZHENG Ying, ZHANG Ying, HAO Chun- xia, KANG Hai-qiong, LU Xiao-lei, YUAN Yuan   

  1. 1. Capital Medical University School of Rehabilitation, Beijing 100068, China; 2. Department of Spinal Cord Injury Rehabilitation, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
  • Published:2016-08-25 Online:2016-09-22

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摘要： 目的回顾分析脊髓损伤患者下肢深静脉血栓预防情况。方法对2015 年4~5 月本院115 例脊髓损伤患者血栓性疾病相关资料进行回顾，收集临床症状、下肢深静脉彩超、实验室检查等资料，分析血栓发生情况及预防措施、血栓发生部位及处理方法。结果在外院曾接受血栓预防43 例，入本院后接受血栓预防105 例。在外院发生有临床症状的下肢深静脉血栓9 例，未发生肺栓塞；在本科发生下肢深静脉血栓者3 例，未发生肺栓塞。外院发生和未发生下肢深静脉血栓患者的大多数实验室指标无显著性差异(P>0.05)。外院曾进行血栓预防措施的患者43 例，未进行过预防的患者72 例，发生下肢深静脉血栓的人数分别是5 例和4例，外院是否行血栓预防措施与血栓发生不相关(χ2=0.663, P=0.415)。53 例完全性脊髓损伤患者中，5 例出现下肢深静脉血栓；59例不完全性脊髓损伤患者中，4 例出现下肢深静脉血栓，发生下肢深静脉血栓与脊髓损伤的严重程度不相关(χ2=0.028, P=0.867)。结论进行血栓预防的患者也会发生下肢深静脉血栓。实验室检查对于预测和诊断下肢深静脉血栓特异性不充分。

关键词: 脊髓损伤, 血栓性疾病, 深静脉血栓, 血栓预防, 回顾分析

Abstract: Objective To retrospectively analyze the lower extremity deep vein thrombosis prevention in patients with spinal cord injury (SCI). Methods A total of 115 SCI patients in our department from April to May, 2015 were included. The clinical symptoms, lower limb deep vein ultrasonic testing, laboratory examination were collected to analyze the occurrence, prevention measures, the thrombus location and management of deep venous thrombosis (DVT) in lower limbs. Results Forty-three patients had thromboprophylaxis in other hospitals before admission, and 105 patients in our department after admission, in which, nine cases were with clinical symptoms in other hospitals and three cases in our department. No pulmonary embolism occurred in them. There was no significant difference in most laboratory indexes between patients with DVT and without DVT in lower limbs (P>0.05). Five patients were with DVT in lower limbs in 43 patients who had thromboprophylaxis, and four cases in 72 patients who did not have thromboprophylaxis. No relationship was found between thromboprophylaxis and DVT in lower limbs (χ2=0.663, P=0.415). Five patients were with DVT in lower limbs in 53 patients with complete SCI, and four cases in 59 patients with incomplete SCI. No relationship was found between the severity of SCI and DVT in lower limbs in other hospitals (χ2=0.028, P=0.867). Conclusion DVT in lower limbs could be also occurred in patients who accepted thromboprophylaxis. Laboratory indexes are inadequate for the prediction and diagnosis specificity of DVT in lower limbs.

Key words: spinal cord injury, thrombotic diseases, deep venous thrombosis, thromboprophylaxis, retrospective analysis