《中国康复理论与实践》

《中国康复理论与实践》

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N-甲基-D-天冬氨酸受体与神经系统疾病关系的研究进展①

杜青，冯珍   

  1. 南昌大学第一附属医院康复医学科，江西南昌市330006。
  • 出版日期:2016-10-25 发布日期:2016-12-05

Advance in Relationship between NMDA Receptors and Neurological Disease (review)

DU Qing, FENG Zhen   

  1. Department of Rehabilitation Medicine, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China
  • Published:2016-10-25 Online:2016-12-05

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摘要： 本文介绍N-甲基-D-天冬氨酸(NMDA)的生物学特性，并对其与神经系统疾病，包括脑外伤、脑缺血、癫痫、神经病理性疼痛、抑郁症和阿尔茨海默病的关系进行综述。

关键词: N-甲基-D-天冬氨酸受体, 神经系统疾病, 发病机制, 综述

Abstract: This article introduced the biological characteristics of N-methyl-D-aspartate (NMDA), and reviewed the relationship between NMDA receptor and neurological disease, including cerebral trauma, cerebral ischemia, epilepsy, neuropathic pain, depression and Alzheimer disease.

Key words: N-methyl-D-aspartate receptor, neurological disease, pathogenesis, review