《中国康复理论与实践》

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老年人糖尿病相关性肌少症的研究进展①

张冰,李维辛   

  1. 兰州大学第一医院老年科二病区,甘肃兰州市730000。
  • 出版日期:2016-11-25 发布日期:2016-12-05

Progress of Diabetes-related Sarcopenia in the Elderly (review)

ZHANG Bing, LI Wei -xin   

  1. The SecondWard in Geriatric Dpartment, the First Hospital of Lanzhou University, Lanzhou, Gansu 730000, China
  • Published:2016-11-25 Online:2016-12-05

摘要: 肌少症是老年糖尿病患者常见的临床并发症之一,可降低患者的生活质量,增加其残疾发生率和疾病死亡率。老年人糖尿病相关性肌少症的发病机制目前尚不明确,除年龄、营养不良因素外,还可能与胰岛素抵抗、慢性炎症、线粒体功能障碍、神经血管系统并发症、血糖控制不佳、血糖高水平及长期用药等有关。规律合适的运动疗法、均衡营养的膳食摄入及降糖药物的合理使用等可促进糖尿病患者肌肉力量的恢复,有望改善其生活质量及预后。

关键词: 老年, 糖尿病, 肌少症, 综述

Abstract: Sarcopenia, also known as skeletal muscle reduction, is one of the common clinical complications of old patients with diabetes, that may impact the quality of life, and increase the incidence of disability and mortality. The pathogenesis of sarcopenia in diabetics is not yet clear, and may associate not only the aging and malnutrition, but also the insulin resistance, chronic inflammation, mitochondrial dysfunction, nerve vascular system complications, poor glycemic control, high blood glucose levels and long-term use medicine about, etc. Regular exercise, balanced nutritional intake and rational use of hypoglycemic drugs can promote the recovery of muscle strength, and may improve the quality of life and outcome of old patients with diabetes.

Key words: old, diabetes mellitus, sarcopenia, review