根除幽门螺杆菌对非酒精性脂肪性肝病的影响

doi:10.3969/j.issn.1006-9771.2017.06.022

《中国康复理论与实践》 ›› 2017, Vol. 23 ›› Issue (6): 725-727.doi: 10.3969/j.issn.1006-9771.2017.06.022

根除幽门螺杆菌对非酒精性脂肪性肝病的影响

张鹏飞, 全丰芝, 杨艳

山东省青岛疗养院,山东青岛市 266071。

收稿日期:2017-01-16 修回日期:2017-04-28 出版日期:2017-06-25 发布日期:2017-06-27
作者简介:张鹏飞(1979-),男,汉族,山东苍山县人,主治医师,主要研究方向：老年医学、康复医学。E-mail: qdlyyzpf@126.com。

Effect of Eradication of Helicobacter Pylori on Non-alcoholic Fatty Liver Disease

ZHANG Peng-fei, QUAN Feng-zhi, YANG Yan

Qingdao Sanatorium of Shandong Province, Qingdao, Shandong 266071, China

Received:2017-01-16 Revised:2017-04-28 Published:2017-06-25 Online:2017-06-27
Contact: Correspondence to ZHANG Peng-fei. E-mail: qdlyyzpf@126.com

摘要/Abstract

摘要： 目的观察是否根除幽门螺杆菌(Hp)对非酒精性脂肪性肝病(NAFLD)程度的影响。方法 2015年12月至2016年4月,选取本院诊断为NAFLD并发Hp感染的患者219例,取119例(观察组)行抗Hp四联治疗,停药1个月后复查¹³C尿素呼气试验,余100例为对照组。两组经6个月的综合康复治疗后行腹部彩超观察NAFLD的程度。结果干预后,观察组Hp根除107例(90.68%),出现肺部感染中止治疗1例。观察组107例Hp根除患者NAFLD程度低于对照组(χ²=8.397, P<0.05)。结论根除Hp并结合综合康复可改善NAFLD程度。

关键词: 非酒精性脂肪性肝病, 幽门螺杆菌, 运动训练, 四联疗法

Abstract: Objective To observe the effect of eradication of helicobacter pylori (Hp) combined with comprehensive rehabilitation treatment on patients with non-alcoholic fatty liver disease (NAFLD). Methods From December, 2015 to April, 2016, 219 patients diagnosed as NAFLD with Hp infection were enrolled, in which 119 patients (observation group) were treated with anti Hp quadruple therapy. They were tested with ¹³C urea breath test one month after drug withdrawal. The other 100 patients were as control group. The severity of NAFLD was observed with abdominal ultrasound after six months. Results After treatment, Hp was eradicated in 107 cases (90.68%) in the observation group, one dropped out for pulmonary infection. After six months, the severity of NAFLD improved better in the patients eradicated Hp in the observation group than in the control group (χ²=8.397, P<0.05). Conclusion Eradication of Hp combined with comprehensive rehabilitation treatment can improve the severity of NAFLD.

Key words: non-alcoholic fatty liver disease, helicobacter pylori, exercise, quadruple therapy

中图分类号:

R575.5

张鹏飞, 全丰芝, 杨艳. 根除幽门螺杆菌对非酒精性脂肪性肝病的影响[J]. 《中国康复理论与实践》, 2017, 23(6): 725-727.

ZHANG Peng-fei, QUAN Feng-zhi, YANG Yan. Effect of Eradication of Helicobacter Pylori on Non-alcoholic Fatty Liver Disease[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2017, 23(6): 725-727.

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根除幽门螺杆菌对非酒精性脂肪性肝病的影响

Effect of Eradication of Helicobacter Pylori on Non-alcoholic Fatty Liver Disease

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