经颅直流电刺激在失语症康复中的应用研究进展

doi:10.3969/j.issn.1006-9771.2018.01.016

《中国康复理论与实践》 ›› 2018, Vol. 24 ›› Issue (1): 84-89.doi: 10.3969/j.issn.1006-9771.2018.01.016

经颅直流电刺激在失语症康复中的应用研究进展

朱苏琼, 顾介鑫

江苏师范大学语言科学与艺术学院,江苏徐州市 221009

收稿日期:2017-10-30 修回日期:2017-12-27 出版日期:2018-01-25 发布日期:2018-01-31
通讯作者: 顾介鑫,男,副教授;E-mail:jiexin.gu@hotmail.com。
作者简介:朱苏琼(1993-),女,汉族,江苏连云港市人,硕士研究生,主要研究方向：神经语言学。
基金资助:
1.国家社会科学基金项目(No. 12CYY021)；2.国家社会科学基金重大招标项目(No. 10&ZD126)；3.江苏高校优势学科建设工程资助项目(PAPD)、江苏高校哲学社会科学重点研究基地重大项目(No. 2012JDXM016)

Advance in Transcranial Direct Current Stimulation for Aphasic Rehabilitation (review)

ZHU Su-qiong, GU Jie-xin

School of Linguistic Sciences and Arts, Jiangsu Normal University, Xuzhou, Jiangsu 221009, China

Received:2017-10-30 Revised:2017-12-27 Published:2018-01-25 Online:2018-01-31
Contact: GU Jie-xin.E-mail:jiexin.gu@hotmail.com
Supported by:
National Social Science Fund of China (No. 12CYY021), National Social Science Fund of China (Major) (No. 10&ZD126) and Priority Academic Program Development of Jiangsu Higher Education Institutions & Research Bases of Philosophy and Social Sciences of Jiangsu Higher Education Institutions (Major) (No. 2012JDXM016)

摘要/Abstract

摘要： 经颅直流电刺激(tDCS)可以有效促进脑卒中后失语症的康复。基于失语症康复三种主要假说,将tDCS应用于失语症临床治疗时,需综合考虑失语症患者大脑左半球的损伤阶段、损伤部位和损伤程度。大脑左半球核心语言功能区未受严重损伤时,宜采用tDCS兴奋大脑左半球以增强病灶周围区兴奋性,使病灶周围区发挥代偿作用;或采用tDCS抑制大脑右半球,以削弱健侧半球对患侧半球的非正常化抑制。大脑左半球核心语言功能区严重损伤时,则宜采用tDCS兴奋大脑右半球,使得大脑右半球发挥代偿作用。此外,还需考虑脑区之间白质纤维束连接是否完整,若白质纤维束受损,tDCS的治疗效果会降低。通过兴奋或抑制大脑皮层的功能,tDCS可增强大脑皮层活动的功能连接,调节脑的神经加工,进而改善失语症患者的词汇检索障碍、发音障碍,提高他们的日常口头交际能力。tDCS的治疗效果具有长期性与普遍化,但仍需进一步探究。

关键词: 失语症, 经颅直流电刺激, 兴奋, 抑制, 康复, 综述

Abstract: Transcranial direct current stimulation (tDCS) was applied in rehabilitation of aphasia effectively. Based on the three hypotheses on aphasic rehabilitation, it is needed to consider the stage, location and the extent of brain damage in the left hemisphere of aphasia patients. If the core language functional areas are not damaged, tDCS can be used to either activate the left hemisphere to enhance the activity of perilesional areas, or to inhibit the right hemisphere to weaken the inhibitory effect from the right one. In contrast, if the core language functional areas are damaged, tDCS should be used to activate the right hemisphere to compensate the left core language functional areas impaired. The integrity of white matter fiber tracts also affects the efficacy of tDCS. By exciting or inhibiting the cortex, tDCS can enhance the cerebral connectivity, and mediate its neural processing, to improve word-retrieval deficit, articulatory disturbance and discourse skill in daily living. The benefit from tDCS may be long-term and generalizated, which needs more researches.

Key words: aphasia, transcranial direct current stimulation, exciting, inhibiting, rehabilitation, review

中图分类号:

R742

朱苏琼, 顾介鑫. 经颅直流电刺激在失语症康复中的应用研究进展[J]. 《中国康复理论与实践》, 2018, 24(1): 84-89.

ZHU Su-qiong, GU Jie-xin. Advance in Transcranial Direct Current Stimulation for Aphasic Rehabilitation (review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2018, 24(1): 84-89.

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经颅直流电刺激在失语症康复中的应用研究进展

Advance in Transcranial Direct Current Stimulation for Aphasic Rehabilitation (review)

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