外泌体在缺血性脑卒中的研究进展

doi:10.3969/j.issn.1006-9771.2018.06.007

《中国康复理论与实践》 ›› 2018, Vol. 24 ›› Issue (6): 654-658.doi: 10.3969/j.issn.1006-9771.2018.06.007

外泌体在缺血性脑卒中的研究进展

李佳帅¹,朱路文²,叶涛¹,李宏玉²,梁碧莹¹,唐强²

1.黑龙江中医药大学,黑龙江哈尔滨市 150040;
2.黑龙江中医药大学附属第二医院,黑龙江哈尔滨市 150001

收稿日期:2018-04-12 修回日期:2018-04-23 出版日期:2018-06-25 发布日期:2018-06-28
通讯作者: 唐强。E-mail: tangqiang1963@163.com
作者简介:李佳帅(1994-),男,汉族,黑龙江伊春市人,硕士研究生,主要研究方向：神经系统疾病中医康复基础。通讯作者：唐强 (1963-),男,汉族,四川大竹县人,博士,教授,主要研究方向：神经系统疾病中医康复基础与临床。
基金资助:
国家自然科学基金项目(No. 81473762)

Research Progress of Exosomes in Ischemic Stroke (review)

LI Jia-shuai¹, ZHU Lu-wen², YE Tao¹, LI Hong-yu², LIANG Bi-ying¹, TANG Qiang²

1. Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China;
2. The Second Hospital Affiliated to Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150001, China

Received:2018-04-12 Revised:2018-04-23 Published:2018-06-25 Online:2018-06-28
Contact: TANG Qiang. E-mail: tangqiang1963@163.com
Supported by:
Supported by National Natural Science Foundation of China (No. 81473762)

摘要/Abstract

摘要： 外泌体是近年来医学领域研究的一大热点,可作为细胞间通信的新载体,在缺血性脑卒中的诊断和治疗方面显示出了极大的潜能。其所含有的microRNA更是在其中扮演重要角色。本文就生物标志物、药物载体、神经血管重塑、治疗等方面,对外泌体在缺血性脑卒中的研究进展做一综述。

关键词: 外泌体, 缺血性脑卒中, microRNA, 神经血管重塑, 综述

Abstract: Exosome is a hot topic in the field of medical research in recent years, which can serve as new carriers for cell-to-cell communication, and show great potential in the diagnosis and treatment of ischemic stroke. microRNA containing in exosomes plays an important role in it. This article reviewed the research progress of exosomes in ischemic stroke on biomarkers, drug carriers, neurovascular remodeling, and treatment.

Key words: exosomes, ischemic stroke, microRNA, neurovascular remodeling, review

中图分类号:

R743.3

李佳帅,朱路文,叶涛,李宏玉,梁碧莹,唐强. 外泌体在缺血性脑卒中的研究进展[J]. 《中国康复理论与实践》, 2018, 24(6): 654-658.

LI Jia-shuai, ZHU Lu-wen, YE Tao, LI Hong-yu, LIANG Bi-ying, TANG Qiang. Research Progress of Exosomes in Ischemic Stroke (review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2018, 24(6): 654-658.

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外泌体在缺血性脑卒中的研究进展

Research Progress of Exosomes in Ischemic Stroke (review)

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