基于汉语高频名词下词图匹配语义判断任务的设计与运用范式

doi:10.3969/j.issn.1006-9771.2018.08.010

《中国康复理论与实践》 ›› 2018, Vol. 24 ›› Issue (8): 917-923.doi: 10.3969/j.issn.1006-9771.2018.08.010

基于汉语高频名词下词图匹配语义判断任务的设计与运用范式

常静玲², 张斌龙, 谭中建, 樊瑞文, 韦宇飞, 高颖²

1.北京中医药大学东直门医院,a.神经内科;b. 放射科,北京市 100700;
2.国家中医药管理局脑病中医证治重点研究室,北京市 100700

收稿日期:2018-04-19 修回日期:2018-07-24 出版日期:2018-08-25 发布日期:2018-08-20
通讯作者: 高颖。E-mail: gaoying973@126.com
作者简介:常静玲(1970-),女,北京市人,回族,主任医师,教授,博士研究生导师,主要研究方向：中医药防治脑病的研究。通讯作者：高颖,女,主任医师,教授,博士研究生导师。
基金资助:
1.国家自然科学基金面上项目(No. 81473654); 2.2014年国家公益性中医药行业科研专项(No. 201407001-9)

Design and Pilot Study of Word-picture Matching Semantic Judgment Task Based on Chinese High Frequency Nouns

CHANG Jing-ling², ZHANG Bin-long, TAN Zhong-jian, FAN Rui-wen, WEI Yu-fei, GAO Ying²

1. a. Department of Neurology; b. Department of Radiology, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China;
2. Key Laboratory of Encephalopathy Treatment of Chinese Medicine, State Administration of Traditional Chinese Medicine, Beijing 100700, China

Received:2018-04-19 Revised:2018-07-24 Published:2018-08-25 Online:2018-08-20
Contact: GAO Ying. E-mail: gaoying973@126.com
Supported by:
Supported by National Science Foundation of China (General) (No. 81473654) and Special Public Welfare Industry and Scientific Research from State Administration of Traditional Chinese Medicine (No. 201407001-9)

摘要/Abstract

摘要： 目的探索基于汉语高频名词的词图匹配语义判断任务的设计思路,以及该任务下的功能磁共振成像(fMRI)和事件相关电位(ERP)实验研究方法,为该领域研究提供范式。方法阐述汉语高频名词的词图匹配判断任务的材料来源和设计流程,并纳入1例健康受试者,进行词图匹配语义判断任务下的fMRI、ERP实验,将任务下采集的fMRI/ERP数据进行分析,判断该任务在fMRI/ERP实验中的可行性。结果 fMRI结果显示,与注视“+”时相比,受试者在词图呈现时右侧额中回激活增高;与词图匹配条件相比,受试者在词图不匹配条件下右侧颞中回激活增高。ERP结果显示,词图匹配条件下受试者左侧额颞区激活较明显,词图不匹配条件下右侧额叶区激活较明显。结论基于本实验设计,采用fMRI、ERP技术均可以获得语言相关脑区激活效应,提示本任务可用于探索汉语语言的脑加工机制。

关键词: 语言, 汉语, 词图匹配, 任务设计

Abstract: Objective To explore the design of word-picture matching semantic judgment task based on Chinese high frequency nouns and further explore the way to apply the task in a functional magnetic resonance imaging (fMRI)/event-related potential (ERP) study.Methods The materials, stimuli and procedure of the word-picture matching semantic task were provided. Then, a healthy subject for the pilot study was included. In the pilot study, fMRI and ERP data of the subject were collected during the word-picture matching task. The fMRI and ERP data were analyzed to test the feasibility of the word-picture matching task in an fMRI/ERP task.Results The results of fMRI analysis showed an increased activity in the right middle frontal gyrus under the word-picture presenting condition compared with the "+" presenting condition. In addition, fMRI analysis showed an increased activity in the right middle temporal gyrus in the word-picture mismatching condition compared with the word-picture matching condition. The results of ERP analysis showed an increased activity in the left frontal/temporal area in the word-picture matching condition and an increased activity in the right frontal area in the word-picture mismatching condition.Conclusion Language associated brain regions can be identified in the fMRI/ERP research based on the word-picture matching task described in this article, which indicated that the task is effective in exploring language processing mechanism in the brain.

Key words: language, Chinese, word-picture matching, task design

中图分类号:

R651.1

常静玲, 张斌龙, 谭中建, 樊瑞文, 韦宇飞, 高颖. 基于汉语高频名词下词图匹配语义判断任务的设计与运用范式[J]. 《中国康复理论与实践》, 2018, 24(8): 917-923.

CHANG Jing-ling, ZHANG Bin-long, TAN Zhong-jian, FAN Rui-wen, WEI Yu-fei, GAO Ying. Design and Pilot Study of Word-picture Matching Semantic Judgment Task Based on Chinese High Frequency Nouns[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2018, 24(8): 917-923.

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基于汉语高频名词下词图匹配语义判断任务的设计与运用范式

Design and Pilot Study of Word-picture Matching Semantic Judgment Task Based on Chinese High Frequency Nouns

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