神经反馈技术在帕金森病治疗中的应用进展

doi:10.3969/j.issn.1006-9771.2018.12.011

《中国康复理论与实践》 ›› 2018, Vol. 24 ›› Issue (12): 1413-1416.doi: 10.3969/j.issn.1006-9771.2018.12.011

神经反馈技术在帕金森病治疗中的应用进展

裴广盈^1a, 闫天翼^1a,b, 方伯言², 吴景龙^1a

1.北京理工大学,a.机电学院;
b.生命学院,北京市 100081;
2.首都医科大学附属北京康复医院,北京市 100144

收稿日期:2018-06-21 修回日期:2018-09-03 出版日期:2018-12-25 发布日期:2019-01-04
通讯作者: 闫天翼(1981-),男,满族,吉林吉林市人,博士,教授,主要研究方向：生物医学工程。闫天翼。E-mail: yantianyi@bit.edu.cn
作者简介:裴广盈(1990-),女,汉族,山东新泰市人,硕士,博士研究生,主要研究方向：神经反馈。
基金资助:
国家自然科学基金项目(No. 81671776; No.61727807)

Application of Neurofeedback for Parkinson's Disease (review)

PEI Guang-ying^1a, YAN Tian-yi^1a,b, FANG Bo-yan², WU Jing-long^1a

1. a. School of Mechatronical Engineering;
b. School of Life Science, Beijing Institute of Technology, Beijing 100081, China;
2. Beijing Rehabilitation Hospital, Capital Medical University, Beijing 100144, China

Received:2018-06-21 Revised:2018-09-03 Published:2018-12-25 Online:2019-01-04
Contact: YAN Tian-yi. E-mail: yantianyi@bit.edu.cn
Supported by:
National Natural Science Foundation of China (No. 81671776 and No.61727807)

摘要/Abstract

摘要： 神经反馈通过调节大脑神经活动,能够改善认知功能和行为表现。神经反馈对帕金森患者的治疗机制主要基于脑电信号和功能磁共振成像血液动力学信号,通过对皮质-脊髓系统异常神经节律振荡(以感觉运动节律为主)进行调节,或以大脑辅助运动区为靶点,调控皮质-基底神经节-丘脑-皮质网络环路。神经反馈能有效改善帕金森患者运动症状,包括动态与静态症状,但研究样本量有限,且训练前后临床症状评估不全面。神经反馈技术可能成为帕金森患者康复的潜在手段。

关键词: 帕金森病, 神经反馈, 脑电图, 功能磁共振成像, 综述

Abstract: Neurofeedback may improve cognitive function and behaviour by regulating the cerebral neural activities. Neurofeedback works as a kind of therapy for patients with Parkinson's disease, primarily based on electroencephalogram signals and hemodynamic signals. It regulates abnormal neuronal rhythm oscillations in the cortical-spinal system by electroencephalogram neurofeedback and sensory motor rhythm as the main adjustment frequency band, and modulates activation in the cortical-basal ganglia-thalamic-cortical network of brain with the supplementary motor area as the target area via functional magnetic resonance imaging neurofeedback. Neurofeedback effectively improves the motor symptoms of Parkinson's patients, both dynamic and static. However, the number of samples is limited in these researches, and the assessments before and after neurofeedback training are not yet comprehensive. Neurofeedback technology might be a potential effective rehabilitation for patients with Parkinson's disease.

Key words: Parkinson's disease, neurofeedback, electroencephalogram, functional magnetic resonance imaging, review

中图分类号:

R742.5

裴广盈, 闫天翼, 方伯言, 吴景龙. 神经反馈技术在帕金森病治疗中的应用进展[J]. 《中国康复理论与实践》, 2018, 24(12): 1413-1416.

PEI Guang-ying, YAN Tian-yi, FANG Bo-yan, WU Jing-long. Application of Neurofeedback for Parkinson's Disease (review)[J]. 《Chinese Journal of Rehabilitation Theory and Practice》, 2018, 24(12): 1413-1416.

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神经反馈技术在帕金森病治疗中的应用进展

Application of Neurofeedback for Parkinson's Disease (review)

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