《中国康复理论与实践》 ›› 2019, Vol. 25 ›› Issue (3): 261-266.doi: 10.3969/j.issn.1006-9771.2019.03.003

• 专题 • 上一篇    下一篇

重复经颅磁刺激治疗阿尔茨海默病的应用进展

黄娜雁1,2, 宋鲁平3, 童志前2, 魏翠柏4, 吕继辉1,2   

  1. 1.北京老年医院精神心理二科,北京市 100095
    2.首都医科大学北京脑重大疾病研究院阿尔茨海默病研究所,北京市 100069
    3.中国康复研究中心北京博爱医院神经内科,北京市 100068
    4.首都医科大学宣武医院神经内科,北京市 100053
  • 收稿日期:2018-05-01 修回日期:2018-06-22 出版日期:2019-03-25 发布日期:2019-04-02
  • 通讯作者: 吕继辉,E-mail: lvjihui@139.com
  • 作者简介:黄娜雁(1995-),女,壮族,广西河池市人,硕士研究生,主要研究方向:老年认知障碍的治疗。通讯作者:吕继辉(1975-),女,汉族,北京市人,博士,主任医师,主要研究方向:老年医学。
  • 基金资助:
    1.首都临床特色应用研究专项(No. Z151100004015023);2.北京市医院管理局临床医学发展专项(No. ZYLX201834)

Advance in Repetitive Transcranial Magnetic Stimulation for Alzheimer's Disease (review)

HUANG Na-yan1,2, SONG Lu-ping3, TONG Zhi-qian2, WEI Cui-bai4, Lü Ji-hui1,2   

  1. 1.Center for Cognitive Disorders, Beijing Geriatric Hospital, Beijing 100095, China
    2.Alzheimer’s Disease Center, Beijing Institute for Brain Disorders, Capital Medical University, Beijing 100069, China
    3.Department of Neurology, Beijing Bo’ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
    4.Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  • Received:2018-05-01 Revised:2018-06-22 Published:2019-03-25 Online:2019-04-02
  • Contact: Lü Ji-hui,corresponding author: E-mail: lvjihui@139.com
  • Supported by:
    Capital Characteristic Clinic Project (No. Z151100004015023) and Beijing Municipal Administration of Hospitals Special Funding for Clinical Medicine Development (No. ZYLX201834)

摘要: 重复经颅磁刺激(rTMS)是一种无痛、无创的皮层刺激方法。rTMS可以通过调节神经可塑性、脑网络,以及神经递质、营养因子等多种途径改善阿尔茨海默病患者的认知功能和精神行为症状。

关键词: 阿尔茨海默病, 重复经颅磁刺激, 认知, 精神, 行为, 综述

Abstract: Repetitive transcranial magnetic stimulation (rTMS), a noninvasive and painless brain stimulation technique, can improve cognition and alleviate behavioral and psychological symptoms in patients with Alzheimer's disease through several mechanisms associated with neuronal plasticity, brain network, neurotransmitter, neurotrophic factors, and so on.

Key words: Alzheimer's disease, repetitive transcranial magnetic stimulation, cognition, psychology, behavior, review

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