《中国康复理论与实践》

《中国康复理论与实践》 ›› 2019, Vol. 25 ›› Issue (12): 1463-1468.doi: 10.3969/j.issn.1006-9771.2019.12.016

• 临床研究 • 上一篇    下一篇

综合康复训练对老年慢性肾脏病并发肌少症的效果

张勃1,2, 吴春薇2, 桂沛君2, 马清3, 张通1,4, 谢瑛2   

  1. 1. 首都医科大学康复医学院，北京市100068
    2.首都医科大学附属北京友谊医院 康复医学科，北京市 100050
    3.首都医科大学附属北京友谊医院，老年医学科，北京市100050
    4.中国康复研究中心北京博爱医院神经康复科，北京市 100068
  • 收稿日期:2019-08-05 修回日期:2019-09-27 出版日期:2019-12-25 发布日期:2019-12-26
  • 通讯作者: 张通，E-mail: zt61611@sohu.com E-mail:zt61611@sohu.com
  • 作者简介:张勃(1972-)，女，汉族，辽宁沈阳市人，副主任技师，主要研究方向：脏器康复、老年康复。
  • 基金资助:
    1.北京市215高层次卫生技术人才学科骨干培训计划项目(No. 2015-3-004)；2.首都医科大学附属北京友谊医院科研启动基金项目(No. Z2018061230015)

Effect of Structured Exercise Training on Old Patients with Chronic Kidney Disease Complicated with Sarcopenia

ZHANG Bo1,2, WU Chun-wei2, GUI Pei-jun2, MA Qing3, ZHANG Tong1,4, XIE Ying2   

  1. 1.Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
    2. Department of Physical Medicine and Rehabilitation Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
    3. Department of Geriatrics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
    4.Department of Neurology, Beijing Bo'ai Hospital, China Rehabilitation Research Centre, Beijing 100068, China
  • Received:2019-08-05 Revised:2019-09-27 Published:2019-12-25 Online:2019-12-26
  • Contact: ZHANG Tong, E-mail: ZT61611@sohu.com E-mail:zt61611@sohu.com
  • Supported by:
    Supported by Program of the High-level technical Talents in Beijing Health System (No. 2015-3-004) and Research Foundation of Beijing Friendship Hospital, Capital Medical University (No. Z2018061230015)

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摘要： 目的 观察低中强度有氧运动联合抗阻运动对老年慢性肾脏病并发肌少症患者的临床疗效。 方法 选取2018年至2019年在本院老年科就诊的慢性肾脏病并发肌少症的老年患者11例，在常规内科治疗的基础上给予低中强度有氧运动联合抗阻运动干预。每运动单元包括有氧运动30~50 min联合抗阻运动20~30 min，每周3次，连续12周。运动前，运动24 h、6周和12周后，测量相关指标。 结果 与运动前比较，首次运动24 h后及6周和12周后，各项血脂和肾功能指标无明显变化(P > 0.05)。与运动前比较，运动6周后座椅前伸试验距离改善(P < 0.05)；运动12周后，四肢骨骼肌质量指数、握力指数、6米步速、峰值摄氧量(VO2peak)、睁眼单腿站立时间、座椅前伸试验距离均改善(P < 0.05)。与运动6周后比较，运动12周后，握力指数、6米步速、VO2peak、睁眼单腿站立时间改善(P < 0.05)。 结论 低中强度有氧运动联合抗阻运动综合康复训练对老年慢性肾脏病并发肌少症患者的肾功能无明显影响，但可以提高其肌肉质量、肌肉力量和运动功能。

关键词: 慢性肾脏病, 肌少症, 老年人, 有氧运动, 抗阻运动

Abstract: Objective To observe the clinical effect of low and medium intensity aerobic exercise combined with resistance exercise on patients with chronic kidney disease (CKD) complicated with sarcopenia. Methods From 2018 to 2019, 11 elderly patients with CKD complicated with sarcopenia were enrolled in this study. All the patients received low and medium intensity aerobic exercise combined with resistance exercise intervention on the basis of regular internal medical treatment. Each exercise section included 30 to 50 minutes of aerobic exercise and 20 to 30 minutes of resistance exercise, and was conducted three times a week for twelve weeks. Before exercise, and 24 hours, six weeks and twelve weeks after exercise, the related indicators were measured. Results No statistical difference in serum lipids and renal function indicators was found 24 hours after exercise, and six and twelve weeks post exercise (P > 0.05). Compared with pre-exercise condition, the reach in seat increased six weeks after exercise (P < 0.05); the appendicular skeletal muscle mass index, the grip strength index, the 6-meter walking speed, the peak oxygen uptake (VO2peak), the one-leg standing time and the reach in seat improved twelve weeks after exercise (P < 0.05). Compared with the results six weeks after exercise, the grip strength index, the 6-meter walking speed, VO2peak and the one-leg standing time improved twelve weeks after exercise (P < 0.05). Conclusion Structured exercise training of low and medium intensity aerobic exercise combined with resistance exercise training would not worsen the renal function of patients with CKD complicated with sarcopenia; however, it could improve the muscle mass, strength and motor function of them.

Key words: chronic kidney disease, sarcopenia, elderly, aerobic training, resistance training

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