《中国康复理论与实践》 ›› 2020, Vol. 26 ›› Issue (1): 67-69.doi: 10.3969/j.issn.1006-9771.2020.01.012

• 综述 • 上一篇    下一篇

阿尔茨海默病视觉障碍研究进展

张静1,2,李晓红1,2(),刘丽军1,2   

  1. 1.大连医科大学,辽宁大连市 116001
    2.大连医科大学附属大连市友谊医院,辽宁大连市 116001
  • 收稿日期:2019-03-15 修回日期:2019-04-30 出版日期:2020-01-25 发布日期:2020-02-07
  • 通讯作者: 李晓红 E-mail:xhlihh@126.com
  • 作者简介:张静(1993-),女,汉族,四川雅安市人,硕士研究生,医师,主要研究方向:帕金森病。|李晓红(1971-),女,汉族,辽宁大连市人,主任医师,主要研究方向:帕金森病。

Advance in Visual Dysfunction for Alzheimer's Disease (review)

ZHANG Jing1,2,LI Xiao-hong1,2(),LIU Li-jun1,2   

  1. 1. Dalian Medical University, Dalian, Liaoning 116001, China
    2. Dalian Friendship Hospital, Dalian Medical University, Dalian, Liaoning 116001, China
  • Received:2019-03-15 Revised:2019-04-30 Published:2020-01-25 Online:2020-02-07
  • Contact: LI Xiao-hong E-mail:xhlihh@126.com

摘要:

近年来发现,阿尔茨海默病(AD)患者视网膜中也存在β-淀粉样蛋白沉积,与颅内改变同步。AD患者存在视敏度和视觉对比敏感度受损、青光眼样视野改变、色觉障碍、视幻觉、视空间受损等功能损害;视网膜厚度变薄,视网膜电图潜伏期延长和振幅减低,视觉诱发电位潜伏期延长。

关键词: 阿尔茨海默病, 视网膜, 视觉, 综述

Abstract:

In recent years, it is found that β-amyloid deposites in the retina of patients with Alzheimer's disease (AD), synchronizing with intracranial changes. AD patients lose their visual acuity and visual contrast sensitivity and demonstrate glaucoma-like visual field loss, color vision disorder, visual hallucination and visual space damage, etc. The retinas become thinner, the latency of electroretinogram prolongs with amplitude decrease, and the latency of visual-evoked potential prolongs.

Key words: Alzheimer's disease, retina, vision, review

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